Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Parcheggio Via Pietransantina | Gare routière de Gerland | CheapestFastest | ||||
| Bus | Parcheggio Via Pietransantina | Gare routière de Gerland | No tags | ||||
| Bus | Parcheggio Via Pietransantina | Gare routière de Gerland | No tags |
Last refresh of the prices: Yesterday at 7:43 AM CEST.
Get from Pisa to Lyon
The journey takes about 13 hours 20 minutes, and with fares starting at just $91, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pisa and Lyon?
Stops in Pisa
- BVia Pietrasantina, 56123 Pisa PI
- C
Piazza della Stazione
Piazza della Stazione, 1, 56125 Pisa PI, Italy
Stops in Lyon
- BRue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
Compare bus companies
Based on 12754 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at $91
Frequently asked questions about travelling from Pisa to Lyon by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Pisa to Lyon?
The cheapest bus tickets from Pisa to Lyon start from $91. The average price for this route is around $155. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Pisa to Lyon?
The average bus travel time from Pisa to Lyon is 13h 20m, covering a distance of 493 km. The quickest bus can get you there in 11h 45m and is operated by FlixBus.
Which bus companies service the Pisa to Lyon route?
Several major bus companies operate on this route with 4 buses available per day.
What are the earliest and latest departure times for the bus from Pisa to Lyon?
The earliest bus departs from Pisa to Lyon at 5:45am. And the latest bus departs at 6:10pm.
What are the CO₂ emissions for the bus trip from Pisa to Lyon?
A bus trip from Pisa to Lyon generates an estimated 12.3064 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Lyon was searched and found on Jun 4, 2026 with a price of $88To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Lyon, as early as possible.
You can expect to pay from $88 to $208 for a bus ticket from Pisa to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $88 which is on 2026-06-04.
