Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Prague (Central Bus Station Florenc) | Mainz | No tags | |||||
| Prague (Main Railway Station) | Mainz | No tags | |||||
| Prague (Central Bus Station Florenc) | Mainz | No tags | |||||
| Prague (Na Knížecí) | Mainz | No tags | |||||
| Prague (Central Bus Station Florenc) | Mainz | No tags |
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Compare 3 ways to go from Prague to Mainz.
Busbud recommends carpooling from Prague to MainzAmong the sustainable travel choices, the carpool stands out as the good way to reach Mainz. The journey takes about 5 hours 30 minutes and with fares starting at just $26, it presents an excellent value for a comfortable ride.
Bus Prague to Mainz: Trip Overview
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Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Prague to Mainz Bus
With Busbud, comparing and booking tickets for a bus from Prague to Mainz is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Prague to Mainz will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Mainz from Prague, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Prague and Mainz?
Frequently asked questions for your trip Prague - Mainz
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Mainz was searched and found on Oct 11, 2025 with a price of $46To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Mainz, as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Prague to Mainz.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Prague to Mainz, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Prague to Mainz.
Tune out to the fine sounds of your best music playlist on your bus trip from Prague to Mainz while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Top traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Prague
Buses Leaving from Prague
- Bus from Prague to Vienna
- Bus Prague - Budapest
- Prague - Tours
- Bus from Prague to Munich
- Bus Prague - Krakow
- Prague - Copenhagen
- Bus from Prague to Telč
- Bus Prague - Žatec
- Prague - Příbram
- Bus from Prague to Jihlava
- Bus Prague - České Budějovice
- Prague - Olomouc
- Bus from Prague to Hradec Králové
- Bus Prague - Vrchlabí
- Prague - Strakonice
Buses Going to Prague
- Bus from Berlin to Prague
- Bus Paris - Prague
- Tours - Prague
- Bus from Amsterdam to Prague
- Bus Krakow - Prague
- Dresden - Prague
- Bus from Pelhrimov to Prague
- Bus Most - Prague
- Liberec - Prague
- Bus from Cheb to Prague
- Bus Žatec - Prague
- Příbram - Prague
- Bus from Špindlerův Mlýn to Prague
- Bus Jičín - Prague
- Písek - Prague
Popular Buses Connecting Mainz
Buses Leaving from Mainz
- Bus from Mainz to Essen
- Bus Mainz - Stuttgart
- Mainz - Strasbourg
- Bus from Mainz to Hahn
- Bus Mainz - Koblenz
- Mainz - Mannheim
- Bus from Mainz to Cologne
- Bus Mainz - Frankfurt am Main
- Mainz - Berlin
- Bus from Mainz to Kaiserslautern
- Bus Mainz - Düsseldorf
- Mainz - Heidelberg
- Bus from Mainz to Aachen
- Bus Mainz - Münster
- Mainz - Bonn
Buses Going to Mainz
- Bus from Dortmund to Mainz
- Bus Augsburg - Mainz
- Bochum - Mainz
- Bus from Bremen to Mainz
- Bus Kiel - Mainz
- Saarbrücken - Mainz
- Bus from Frankfurt am Main to Mainz
- Bus Berlin - Mainz
- Stuttgart - Mainz
- Bus from Hahn to Mainz
- Bus Simmern - Mainz
- Düsseldorf - Mainz
- Bus from Cologne to Mainz
- Bus Mannheim - Mainz
- Trier - Mainz
Popular routes in this country
- Bus from Brno to Prague
- Bus Jihlava - Prague
- Telč - Brno
- Bus from Prague to Pec pod Sněžkou
- Bus Jihlava - Olomouc
- Karlovy Vary - Cheb
- Bus from Třeboň to Český Krumlov
- Bus Hradec Králové - Litomyšl
- Znojmo - Prague
- Bus from Ostrava to Prague
- Bus Hradec Králové - Trutnov
- Ostrava - Nový Jičín
- Bus from Hradec Králové to Brno
- Bus Hradec Králové - Liberec
- Prague - Liberec