Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Prague (Central Bus Station Florenc) | Mainz | No tags | ||||
| Bus | Prague (Na Knížecí) | Mainz | No tags | ||||
| Bus | Prague (Main Railway Station) | Mainz | No tags | ||||
| Bus | Prague (Central Bus Station Florenc) | Mainz | No tags | ||||
| Bus | PRG Airport | Mainz | No tags |
Compare 3 ways to travel from Prague to Mainz
Among the sustainable travel choices, the Carpool stands out as a good way to reach Mainz. The journey takes about 5 hours and with fares starting at just £20, it presents an excellent value for a comfortable ride.
Where are the popular stops in Prague and Mainz?
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- CChlumecká, 198 00 Praha 20, Czech Republic
- DTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Mainz
- A
Mainz
Hechtsheimer Str. 65, 55131 Mainz, Germany - B
Mainz- Kaiser-Wilhelm-Ring 16- gegenüberliegende Straßenseite
Kaiser-Wilhelm-Ring 16 (gegenüberliegende Straßenseite), 55118 Mainz - Cflibco.com bus stop, Kaiser-Wilhelm-Ring, 55118 Mainz, Germany
Compare bus companies
Based on 12214 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at £36
Frequently asked questions about travelling by bus from Prague to Mainz
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Prague to Mainz?
The cheapest coach tickets from Prague to Mainz start from £36. The average price for this route is around £44. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Prague to Mainz?
The average bus journey time from Prague to Mainz is 10h 10m, covering a distance of 274 miles. The fastest bus can take you there in 8h 5m and is operated by FlixBus.
Which bus companies service the Prague to Mainz route?
Several major bus companies operate on this route with 8 buses available per day.
What is the earliest and latest departure time for the bus from Prague to Mainz?
The earliest bus departs from Prague to Mainz at 03:50. And the latest bus departs at 22:45.
What are the CO₂ emissions for the bus trip from Prague to Mainz?
A bus journey from Prague to Mainz produces an estimated 11 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Mainz was searched and found on 14 Feb 2026 with a price of £37To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Mainz as early as possible.
