Train from Florence, SC, US to Chicago: Tickets & Schedules

Next train departures

Next departures for Florence to Chicago on April 30
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Florence Station
Chicago (Union Station), ILCheapestFastest
AmtrakTrain
Florence Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Florence Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Florence Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Florence Station
Chicago (Union Station), ILNo tags

Last refresh of the prices: Yesterday at 6:12 AM EDT.

Compare 2 ways to go from Florence to Chicago

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Chicago. The journey takes about 1 day, 3 hours 25 minutes and with fares starting at just CA$125, it presents an excellent value for a comfortable ride.

11bus per day
1d 3hAverage Duration
678 milesDistance
27kgCO₂ emissions
Average PriceCA$125 - CA$573Average Duration1d 3h
27kg CO₂e
Average PriceCA$441 - CA$1,678Average Duration1d 12h
100kg CO₂e

Frequently asked questions about traveling from Florence, SC, US to Chicago by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Florence to Chicago?

    The cheapest train tickets from Florence to Chicago start from CA$441. The average price for this train route is around CA$657. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the train journey from Florence to Chicago?

    The average train ride duration from Florence to Chicago is 1d 12h, covering a distance of 681 miles (1098 km). The quickest train can get you there in 1d 11h and is operated by Amtrak.

  3. Which train operators service the Florence to Chicago route?

    Several major train operators operate on this route with 2 trains available per day.

  4. What is the earliest and latest departure time for the train from Florence to Chicago?

    The earliest train departs from Florence to Chicago at 10:32pm. And the latest train departs at 10:32pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/28
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04/29
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Today
CA$636
05/01
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05/02
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05/03
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busbud logoThe cheapest trip from Florence, SC, US to Chicago was searched and found on Apr 30, 2026 with a price of CA$636

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Chicago, as early as possible.

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