Trains tickets from Charleston, SC, US to Harrisburg

Discover your next train travel journey from Charleston, SC, US to Harrisburg and book online with ease

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJul 17
TomorrowJul 18
SatJul 19
SunJul 20
MonJul 21
from $273
TueJul 22
WedJul 23
ThuJul 24

Trains leaving Monday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 21 at
    Departure city: Charleston
    Departure location: Charleston Station
    Arrival time: July 22 at
    Destination city: Harrisburg
    Destination location: Harrisburg, PA
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 21 at
    Departure city: Charleston
    Departure location: Charleston Station
    Arrival time: July 22 at
    Destination city: Harrisburg
    Destination location: Harrisburg, PA
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: July 21 at
    Departure city: Charleston
    Departure location: Charleston Station
    Arrival time: July 22 at
    Destination city: Harrisburg
    Destination location: Harrisburg, PA
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: July 21 at
    Departure city: Charleston
    Departure location: Charleston Station
    Arrival time: July 22 at
    Destination city: Harrisburg
    Destination location: Harrisburg, PA
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: July 21 at
    Departure city: Charleston
    Departure location: Charleston Station
    Arrival time: July 22 at
    Destination city: Harrisburg
    Destination location: Harrisburg, PA
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Charleston to Harrisburg.

Average Price$150 - $252Average Duration23h 40m
22kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average Price$165 - $327Average Duration16h 52m
79kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Charleston to Harrisburg

Among the sustainable travel choices, the bus stands out as the good way to reach Harrisburg. The journey takes about 23 hours 40 minutes and with fares starting at just $150, it presents an excellent value for a comfortable ride.

3bus per day
23h 40mAverage Duration
$150Cheapest ticket
22kgCO₂ emissions

Train Charleston, SC, US to Harrisburg: Trip Overview

Please note, this information is subject to change.

Average ticket price$273
Average train trip duration16h 52m
Number of daily trains1
Earliest train departure9:34pm
Distance538 miles (867 km)

Charleston to Harrisburg Train

With Busbud, comparing and booking tickets for a train from Charleston to Harrisburg is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.

Train service from Charleston to Harrisburg will be provided by the most trusted companies.

Whether it is train tickets or first class train tickets going to Harrisburg from Charleston, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Charleston, SC, US - Harrisburg

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/15
$314
07/16
No data
Today
$314
07/18
No data
07/19
No data
07/20
No data
07/21
$262
07/22
No data
busbud logoThe cheapest trip from Charleston to Harrisburg was searched and found on Jul 21, 2025 with a price of $262

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Charleston to Harrisburg, as early as possible.

You can expect to pay from $262 to $690 for a train ticket from Charleston to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $262 which is on 2025-07-21.

About Train Travel

Train Travel Tips

Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Charleston to Harrisburg is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.

No matter if you plan to take a regional or high-speed train to Harrisburg, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.

By choosing the train between Charleston and Harrisburg, you emit up to 30 times less CO2 than for the same journey made by plane or car!

Make a music playlist for your train ride from Charleston to Harrisburg, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.

Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.

Railway companies played a major role as early as 1883 in the use of time zones as we know them today.

Will you be returning to Charleston, SC, US by train?

Train from Harrisburg to Charleston, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

Popular Trains Connecting Charleston

Trains Leaving from Charleston

Popular Trains Connecting Harrisburg

Trains Going to Harrisburg