Compare 2 ways to go from Charleston to Indianapolis.
Busbud recommends taking the bus from Charleston to IndianapolisAmong the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 20 hours 50 minutes and with fares starting at just $150, it presents an excellent value for a comfortable ride.
Train Charleston to Indianapolis: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5212 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $482.00
Charleston to Indianapolis Train
With Busbud, comparing and booking tickets for a train from Charleston to Indianapolis is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make it our job to connect you with the most dependable companies that offer train service from Charleston to Indianapolis.
Whether it is train tickets or first class train tickets going to Indianapolis from Charleston, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Charleston (SC), US - Indianapolis
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charleston to Indianapolis was searched and found on Jun 17, 2025 with a price of $359To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Charleston to Indianapolis, as early as possible.
You can expect to pay from $359 to $1,436 for a train ticket from Charleston to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $1,436 which is on 2025-06-19.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Charleston to Indianapolis is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Whether you take a regional or high-speed train to Indianapolis, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between Charleston and Indianapolis, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Make a music playlist for your train ride from Charleston to Indianapolis, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Railway companies played a major role as early as 1883 in the use of time zones as we know them today.
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.
Top Traveled Train Routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Trains Connecting Charleston
Trains Leaving from Charleston
Popular Trains Connecting Indianapolis
Trains Going to Indianapolis
Popular train trips
Top Routes Worldwide
- Train from Wells to Fargo
- Train from Richmond to Richmond
- Train from Detroit to Red Wing
- Train from Wilmington to Wilmington
- Train from Los Angeles to Glendale
- Train from Niagara Falls to Ontario
- Train from Washington to Leavenworth
- Train from Waterloo to Buffalo
- Train from New York to Saratoga Springs
- Train from Saratoga Springs to New York
- Train from Washington to Everett
- Train from Seattle to Washington
- Train from Salem to Washington
- Train from Jacksonville to Jacksonville
- Train from Vancouver to Washington