Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Greyhound Amtrak Station | Greenville Station | No tags | |||||
| Greyhound Amtrak Station | Greenville Station | No tags | |||||
| Greyhound Amtrak Station | Greenville Station | No tags | |||||
| Greyhound Amtrak Station | Greenville Station | No tags | |||||
| Greyhound Amtrak Station | Greenville Station | No tags |
Accepted payments
Compare 2 ways to go from Indianapolis to Greenville
Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 16 hours 15 minutes and with fares starting at just $70, it presents an excellent value for a comfortable ride.
Train Indianapolis to Greenville, SC: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5562 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $156
Indianapolis to Greenville Train
With Busbud, comparing and booking tickets for a train from Indianapolis to Greenville is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make sure you can find a train service from Indianapolis to Greenville from the most reliable train companies operating this trip.
Whether it is train tickets or first class train tickets going to Greenville from Indianapolis, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Indianapolis - Greenville, SC
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Greenville, SC was searched and found on Nov 2, 2025 with a price of $133To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Indianapolis to Greenville, SC, as early as possible.
You can expect to pay from $133 to $894 for a train ticket from Indianapolis to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $149 which is on 2025-11-07.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Indianapolis to Greenville is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Regional train? High-speed train? Whichever train to Greenville you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between Indianapolis and Greenville, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Tune out to the fine sounds of your best music playlist on your train trip from Indianapolis to Greenville while indulging in miles on end of beautiful scenic views.
Did you know?
New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.
Japanese trains are always on time, it is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologize to each passenger.
The first high-speed train line was inaugurated in 1964, in Japan, to connect Tokyo with Osaka. It was during the Olympics that the first passengers traveled aboard the Shinkansen at a speed of 210 km / h.
Top Traveled Train Routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Trains Connecting Indianapolis
Trains Leaving from Indianapolis
Popular Trains Connecting Greenville
Trains Going to Greenville
Popular train trips
Top Routes Worldwide
- Train from Wells to Fargo
- Train from Columbia to New York City
- Train from Detroit to Red Wing
- Train from Holland to Taylor
- Train from Los Angeles to Glendale
- Train from Waterloo to Buffalo
- Train from Niagara Falls to Ontario
- Train from Washington to Leavenworth
- Train from Washington to Everett
- Train from Buffalo to New York City
- Train from Seattle to Washington
- Train from Rochester to New York City
- Train from Vancouver to Washington
- Train from Ventura to Simi Valley
- Train from Newark to Essex