Train tickets from Spartanburg to Chicago

Previously seen trips

Next departures for Spartanburg to Chicago on November 19
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Spartanburg Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Spartanburg Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Spartanburg Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Spartanburg Station
Chicago (Union Station), ILNo tags
AmtrakTrain
Spartanburg Station
Chicago (Union Station), ILNo tags

Compare 2 ways to go from Spartanburg to Chicago

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 20 hours 30 minutes and with fares starting at just $119, it presents an excellent value for a comfortable ride.

9bus per day
20h 30mAverage Duration
554 milesDistance
22kgCO₂ emissions
Average Price$119 - $291Average Duration20h 30m
22kg CO₂e
Average Price$208 - $1,577Average Duration1d 6h
83kg CO₂e

Frequently asked questions about traveling from Spartanburg to Chicago by train

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/17
$379
11/18
No data
Today
$288
11/20
No data
11/21
No data
11/22
No data
11/23
No data
11/24
No data
busbud logoThe cheapest trip from Spartanburg to Chicago was searched and found on Nov 19, 2025 with a price of $288

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Spartanburg to Chicago, as early as possible.

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