Bus Tickets from Columbus (OH) to Panama City, US

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TodayMay 25
TomorrowMay 26
TueMay 27
from US$116
WedMay 28
ThuMay 29
FriMay 30
SatMay 31
SunJun 1

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: May 27 at
    Departure city: Columbus
    Departure location: 100 E Rich St
    Arrival time: May 28 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 27 at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: May 28 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 27 at
    Departure city: Columbus
    Departure location: Columbus (E Mound St)
    Arrival time: May 29 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Thursday at 7:30 PM EDT.

Prices and availability are subject to change.

Accepted payments

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Bus Columbus to Panama City: Trip Overview

Average Ticket PriceUS$151
Average Bus Trip Duration1d 8h
Number of daily buses3
Earliest bus departure5:30am
Distance1115 km
Latest bus departure10:05pm

Columbus to Panama City Bus

With Busbud, comparing and booking tickets for a bus from Columbus to Panama City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Columbus to Panama City from the most reliable bus companies operating this trip.

Discover how much the bus trip from Columbus to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Columbus (OH) - Panama City, US

  1. How long is the bus ride from Columbus to Panama City?

    The bus ride from Columbus to Panama City takes 1d 8h, on average. For the shortest travel time, select the fastest bus available, which will take you to Panama City in about 1d 3h.

  2. How far is Columbus from Panama City?

    Columbus and Panama City are 1118 km (693 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Columbus to Panama City?

    Buses departing from Columbus Bus Station in Columbus will take you to Panama City Greyhound Bus Station in Panama City.

  4. What is the cheapest way to get from Columbus to Panama City?

    Taking the bus is the most budget-friendly option to travel from Columbus to Panama City. Starting at US$141, this bus is the most cost-effective option for your journey.

  5. How much does it cost to take the bus from Columbus to Panama City?

    The bus from Columbus to Panama City will cost you US$151, on average.

  6. Can I take an overnight bus from Columbus to Panama City?

    Yes! If you're heading from Columbus to Panama City, you'll find buses departing until 10:05pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-23
No data
05-24
No data
Today
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05-26
No data
05-27
US$110
05-28
No data
05-29
No data
05-30
No data
busbud logoThe cheapest trip from Columbus to Panama City was searched and found on May 27, 2025 with a price of US$110

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus to Panama City, as early as possible.

You can expect to pay from US$110 to US$110 for a bus ticket from Columbus to Panama City based on the last 2 days. You can expect to find the cheapest price for the trip at US$110 which is on 2025-05-27.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Columbus to Panama City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Columbus to Panama City, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Columbus to Panama City will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Columbus to Panama City.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Columbus by bus?

Bus from Columbus to Panama City

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