Bus Tickets from Frankfurt am Main to Prague

Next departures

Next departures for Frankfurt am Main to Prague on November 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
KLR Bus
    		Frankfurt Main Airport P36
    		FlorencCheapest
    RegioJet
      		Frankfurt - Main bus station
      		FlorencFastest
      Flixbus
        		Frankfurt Hbf
        		PRG AirportNo tags
        KLR Bus
          		Frankfurt Main Train Station
          		FlorencNo tags
          Flixbus
            		FRA Frankfurt airport
            		PRG AirportNo tags

            Last refresh of the prices: Yesterday at 11:51 PM CET.

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            Compare 3 ways to go from Frankfurt am Main to Prague

            We recommend carpooling

            Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours 20 minutes, and with fares starting at just $37, it presents an excellent value for a comfortable ride.

            3carpool per day
            5h 20mAverage Duration
            410 kmDistance
            17kgCO₂ emissions
            Bus
            		Average Price$27 - $261Average Duration8h 56m
            10kg CO₂e
            Train
            		Average Price$52 - $381Average Duration7h 9m
            10kg CO₂e
            Carpool
            		Average Price$37 - $95Average Duration5h 20m
            17kg CO₂e

            Bus Frankfurt am Main to Prague: Trip Overview

            Average Ticket Price$62
            Average Bus Trip Duration8h 56m
            Number of daily buses26
            Earliest bus departure12:20am
            Distance409 km
            Latest bus departure11:59pm

            Frankfurt am Main to Prague Bus

            With Busbud, comparing and booking tickets for a bus from Frankfurt am Main to Prague is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            Bus service from Frankfurt am Main to Prague will be provided by the most trusted bus companies.

            From cheap bus tickets to more luxurious buses travelling from Frankfurt am Main to Prague, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions on the trip Frankfurt am Main - Prague

            1. What is the travel distance from Frankfurt am Main to Prague?

              The distance covered from Frankfurt am Main to Prague is 410 km (254 miles).

            2. What are the departure and arrival locations for buses traveling from Frankfurt am Main to Prague?

              Buses traveling this route start their trip at Frankfurt Airport, in Frankfurt am Main, and end it at Florenc, in Prague.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            11-02
            $62
            11-03
            $51
            Today
            $25
            11-05
            $29
            11-06
            $46
            11-07
            $29
            11-08
            $45
            11-09
            $25
            busbud logoThe cheapest trip from Frankfurt am Main to Prague was searched and found on Nov 4, 2025 with a price of $25

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frankfurt am Main to Prague, as early as possible.

            You can expect to pay from $25 to $148 for a bus ticket from Frankfurt am Main to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $25 which is on 2025-11-09.

            Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while travelling from Frankfurt am Main to Prague.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Much more than a mere vehicle taking you from Frankfurt am Main to Prague, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Frankfurt am Main to Prague that are otherwise impossible to come by with a plane.

            Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Frankfurt am Main to Prague.

            Did you know?

            The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

            9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

            The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

            What's the cheapest way to go from Frankfurt am Main to Prague?

            busbud logoThe bus is the cheapest travel choice for this destination

            Will you be returning to Frankfurt am Main by bus?

            Bus from Prague to Frankfurt am Main

            You can also go to Prague by train

            Train from Frankfurt am Main to Prague

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