Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rosa Parks Station | Chicago 95Th & Dan Ryan | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Rosa Parks Station | Downtown Greyhound Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gainesville Bus Stop | Downtown Greyhound Station | No tags | ||||
| Bus | Rosa Parks Station | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gainesville Bus Stop | 537-517 W. Jackson Blvd | No tags |
Last refresh of the prices: Yesterday at 12:18 AM EST.
Get from Gainesville to Chicago
The journey takes about 1 day, 1 hour 25 minutes, and with fares starting at just $154, it presents an excellent value for a comfortable ride.
Where are the popular stops in Gainesville and Chicago?
Stops in Gainesville
- A700 SE 3rd St, Gainesville, FL 32601
- B3509 SW Williston Rd, Gainesville, FL 32608, USA
- C101 NE 23rd Ave, Gainesville, FL 32609
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Frequently asked questions about travelling from Gainesville, FL to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Gainesville to Chicago?
The cheapest bus tickets from Gainesville to Chicago start from $154. The average price for this route is around $301. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Gainesville to Chicago?
The average bus travel time from Gainesville to Chicago is 1d 1h, covering a distance of 1442 km. The quickest bus can get you there in 22h 10m and is operated by FlixBus.
Which bus companies service the Gainesville to Chicago route?
What are the earliest and latest departure times for the bus from Gainesville to Chicago?
The earliest bus departs from Gainesville to Chicago at 1:10am. And the latest bus departs at 10:40pm.
What are the CO₂ emissions for the bus trip from Gainesville to Chicago?
A bus trip from Gainesville to Chicago generates an estimated 36 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Gainesville to Chicago?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11638 reviews.
Which bus company has the best Wi-Fi from Gainesville to Chicago?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Gainesville to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Gainesville to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Gainesville, FL to Chicago was searched and found on Dec 21, 2025 with a price of $374To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Chicago, as early as possible.
