Bus Tickets from Gainesville, FL to Chicago

Find affordable bus tickets from Gainesville, FL to Chicago with flexible options. Book your trip now

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TodayJun 20
from $147
TomorrowJun 21
from $124
SunJun 22
from $118
MonJun 23
from $143
TueJun 24
from $144
WedJun 25
from $114
ThuJun 26
from $126
FriJun 27

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 21 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: June 22 at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 21 at
    Departure city: Gainesville
    Departure location: Rosa Parks Station
    Arrival time: June 22 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 21 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: June 22 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 21 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: June 22 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: June 21 at
    Departure city: Gainesville
    Departure location: Rosa Parks Station
    Arrival time: June 22 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Bus Gainesville to Chicago: Trip Overview

Average ticket price$150
Average bus trip duration1d 3h
Number of daily buses26.631578947368425
Earliest bus departure12:25am
Distance894 miles (1441 km)
Latest bus departure10:40pm

Gainesville to Chicago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Gainesville to Chicago.

We make it our job to connect you with the most dependable bus companies that cover bus service from Gainesville to Chicago.

Whether it is cheap bus tickets or more luxurious buses going to Chicago from Gainesville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Gainesville, FL - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/18
$134
06/19
$112
Today
$140
06/21
$117
06/22
$110
06/23
$135
06/24
$136
06/25
$108
busbud logoThe cheapest trip from Gainesville to Chicago was searched and found on Jun 25, 2025 with a price of $108

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville to Chicago, as early as possible.

You can expect to pay from $108 to $238 for a bus ticket from Gainesville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $108 which is on 2025-06-25.

Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Gainesville to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Gainesville to Chicago.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Gainesville to Chicago.

Tune out to the fine sounds of your best music playlist on your bus trip from Gainesville to Chicago while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Gainesville by bus?

Bus from Gainesville to Chicago

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