Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Harrisburg Bus Station | Indianapolis Bus Station | Cheapest | ||||
| Bus | Harrisburg Bus Station | Indianapolis Bus Station | Fastest | ||||
| Bus | Harrisburg Bus Station | Indianapolis Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Harrisburg Bus Station | Downtown Transit Center | No tags | ||||
| Bus | Harrisburg Bus Station | Indianapolis Bus Station | No tags |
Last refresh of the prices: Yesterday at 8:40 PM EST.
Compare 2 ways to go from Harrisburg to Indianapolis
Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 14 hours, and with fares starting at just $101, it presents an excellent value for a comfortable ride.
Where are the popular stops in Harrisburg and Indianapolis?
Stops in Harrisburg
- A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101
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Frequently asked questions about travelling from Harrisburg to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Harrisburg to Indianapolis?
The cheapest bus tickets from Harrisburg to Indianapolis start from $101. The average price for this route is around $170. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Harrisburg to Indianapolis?
The average bus travel time from Harrisburg to Indianapolis is 14h, covering a distance of 793 km. The quickest bus can get you there in 11h 10m and is operated by Greyhound.
Which bus companies service the Harrisburg to Indianapolis route?
What are the earliest and latest departure times for the bus from Harrisburg to Indianapolis?
The earliest bus departs from Harrisburg to Indianapolis at 1:30am. And the latest bus departs at 9:10pm.
What are the CO₂ emissions for the bus trip from Harrisburg to Indianapolis?
A bus trip from Harrisburg to Indianapolis generates an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Harrisburg to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Harrisburg to Indianapolis?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Harrisburg to Indianapolis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Harrisburg to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Harrisburg to Indianapolis was searched and found on Dec 4, 2025 with a price of $91To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Indianapolis, as early as possible.
You can expect to pay from $91 to $530 for a bus ticket from Harrisburg to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $91 which is on 2025-12-04.
What's the cheapest way to go from Harrisburg to Indianapolis?
The bus is the cheapest travel choice for this destination
