Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal de Omnibus Huasco | San Borja | No tags | ||||
| Bus | Terminal de Omnibus Huasco | San Borja | No tags | ||||
| Bus | Terminal de Omnibus Huasco | San Borja | No tags | ||||
| Bus | Terminal de Omnibus Huasco | San Borja | No tags | ||||
| Bus | Terminal de Omnibus Huasco | San Borja | No tags |
Get from Huasco to Santiago
This route is served by bus only
The journey takes about 10 hours 5 minutes, and with fares starting at just $45, it presents an excellent value for a comfortable ride.
1bus per day
10h 5mAverage Duration
557 kmDistance
14kgCO₂ emissions
Where are the popular stops in Huasco and Santiago?
Stops in Huasco
- AHuasco - Guacolda 657, Huasco, III Región, Chile
Stops in Santiago
- A
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile - BSantiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
- CTucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
- DPdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
- EAv. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
- F
Santiago
Juan Esteban Montero 5688, Las Condes, Las Condes, Región Metropolitana, Chile
Compare bus companies
4 out of 5 stars4/512 reviews
Based on 12 reviews, Serena Mar was rated 4 stars for this trip. Serena Mar ticket prices on this trip start at $45, with the trip lasting on average 605.
CL Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about travelling from Huasco to Santiago, CL by bus
What is the distance between Huasco and Santiago?
Huasco and Santiago are 556 km (345 miles) apart.
What are the departure and arrival locations for buses traveling from Huasco to Santiago?
Buses departing from Terminal de Omnibus Huasco in Huasco will take you to San Borja in Santiago.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-22
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11-23
$42
Today
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11-25
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11-26
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11-27
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11-28
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11-29
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The cheapest trip from Huasco to Santiago, CL was searched and found on Nov 23, 2025 with a price of $42To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Huasco to Santiago, CL, as early as possible.
