Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal De Buses La Paz | Santa Cruz de la Sierra | CheapestFastest | ||||
| Bus | Terminal De Buses La Paz | Santa Cruz de la Sierra | No tags | ||||
 | Bus | Terminal De Buses La Paz | Santa Cruz de la Sierra | No tags | ||||
 | Bus | Terminal De Buses La Paz | Santa Cruz de la Sierra | No tags | ||||
Trans Copacabana 1 MEM + Flota Capital | Bus | Terminal De Buses La Paz | Santa Cruz de la Sierra | No tags |
Last refresh of the prices: Today at 4:33 PM -04.
Get from La Paz to Santa Cruz de la Sierra
The journey takes about 20 hours, and with fares starting at just $55, it presents an excellent value for a comfortable ride.
Where are the popular stops in La Paz and Santa Cruz de la Sierra?
Stops in Santa Cruz de la Sierra
- AAv Intermodal, Santa Cruz de la Sierra, Bolivia
Compare bus companies
Frequently asked questions about travelling from La Paz, BO to Santa Cruz de la Sierra, BO by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from La Paz to Santa Cruz de la Sierra?
The cheapest bus tickets from La Paz to Santa Cruz de la Sierra start from $55. The average price for this route is around $62. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from La Paz to Santa Cruz de la Sierra?
The average bus travel time from La Paz to Santa Cruz de la Sierra is 20h, covering a distance of 549 km. The quickest bus can get you there in 20h and is operated by Trans Copacabana MEM 1.
Which bus companies service the La Paz to Santa Cruz de la Sierra route?
Several major bus companies operate on this route with 13 buses available per day, including services from Trans Copacabana MEM 1, Trans Copacabana S.A., Transportes el Dorado, 6 de Octubre.
What are the earliest and latest departure times for the bus from La Paz to Santa Cruz de la Sierra?
The earliest bus departs from La Paz to Santa Cruz de la Sierra at 12:00pm. And the latest bus departs at 8:30pm.
What are the CO₂ emissions for the bus trip from La Paz to Santa Cruz de la Sierra?
A bus trip from La Paz to Santa Cruz de la Sierra generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from La Paz to Santa Cruz de la Sierra?
According to Busbud customers, the highest-rated bus company on this route is Transportes el Dorado, with an average rating of 3.2 out of 5 stars based on 9 reviews.
Which bus company has the best Wi-Fi from La Paz to Santa Cruz de la Sierra?
Based on Busbud reviews, the bus company Trans Copacabana S.A. has the highest Wi-Fi rating with a score of 0.2.
Which bus company has the best on-time performance from La Paz to Santa Cruz de la Sierra?
According to Busbud traveller reviews, the most punctual bus company on this route is Transportes el Dorado, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from La Paz to Santa Cruz de la Sierra?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Trans Copacabana MEM 1, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from La Paz, BO to Santa Cruz de la Sierra, BO was searched and found on Dec 7, 2025 with a price of $52To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Paz, BO to Santa Cruz de la Sierra, BO, as early as possible.
You can expect to pay from $52 to $59 for a bus ticket from La Paz, BO to Santa Cruz de la Sierra, BO based on the last 2 days. You can expect to find the cheapest price for the trip at $52 which is on 2025-12-10.
Usually Transportes el Dorado will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
