Bus Tickets from La Serena, CL to San Antonio, CL

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Bus La Serena to San Antonio: Trip Overview

Average Ticket PriceUS$18
Average Bus Trip Duration9h 25m
Number of daily buses6
Earliest bus departure6:00am
Distance411 km
Latest bus departure11:59pm

La Serena to San Antonio Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from La Serena to San Antonio.

We make sure you can find a bus service from La Serena to San Antonio from the most reliable bus companies operating this trip.

Discover how much the bus trip from La Serena to San Antonio will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip La Serena, CL - San Antonio, CL

  1. What is the travel distance from La Serena to San Antonio?

    The distance between La Serena and San Antonio is approximately 413 km (256 miles).

  2. What are the departure and arrival locations for buses traveling from La Serena to San Antonio?

    Buses departing from Terminal de Buses La Serena in La Serena will take you to Terminal Barrancas de San Antonio in San Antonio.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-09
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Today
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07-12
US$17
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busbud logoThe cheapest trip from La Serena to San Antonio was searched and found on Jul 12, 2025 with a price of US$17

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena to San Antonio, as early as possible.

You can expect to pay from US$17 to US$20 for a bus ticket from La Serena to San Antonio based on the last 2 days. You can expect to find the cheapest price for the trip at US$17 which is on 2025-07-12.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from La Serena to San Antonio but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from La Serena to San Antonio, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from La Serena to San Antonio will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from La Serena to San Antonio.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to La Serena by bus?

Bus from La Serena to San Antonio

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