What is the travel distance from Luxembourg to Lyon?

It's about 443 km (275 miles) from Luxembourg to Lyon.

What are the departure and arrival locations for buses traveling from Luxembourg to Lyon?

Buses departing from Luxembourg in Luxembourg will take you to Perrache in Lyon.

Bus Luxembourg to Lyon from $43 | Refundable Tickets

Next bus departures

Next departures for Luxembourg to Lyon on November 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	3:00am	Luxembourg	17h 35m	8:35pm	Perrache	Cheapest
	Bus	12:25pm	Luxembourg	14h 55m	3:20am	Perrache	Fastest

Next departures for Luxembourg to Lyon on November 28
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	3:35am	Luxembourg	14h 45m	6:20pm	Perrache	Cheapest
Bus	10:55am	Luxembourg	12h 20m	11:15pm	Perrache	Fastest
Bus	2:25am	Luxembourg	20h 30m	10:55pm	Lyon - Perrache Bus Station	No tags
Bus	2:10am	Luxembourg	13h 10m	3:20pm	Perrache	No tags
Bus	10:50pm	Luxembourg	18h 20m	5:10pm	Lyon - Perrache Bus Station	No tags

Next departures for Luxembourg to Lyon on November 29
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	9:00pm	Luxembourg	7h 45m	4:45am	Perrache	CheapestFastest
Bus	2:25am	Luxembourg	20h 30m	10:55pm	Lyon - Perrache Bus Station	No tags
Bus	10:50pm	Luxembourg	18h 20m	5:10pm	Lyon - Perrache Bus Station	No tags

Last refresh of the prices: Last Wednesday at 8:28 AM CET.

Compare 3 ways to go from Luxembourg to Lyon

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 5 hours 20 minutes, and with fares starting at just $56, it presents an excellent value for a comfortable ride.

3carpool per day

5h 20mAverage Duration

440 kmDistance

18kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$49 - $268	Average Duration10h 45m	CO₂ emissions 11kg CO₂e
Train	Average Price$86 - $414	Average Duration5h 46m	CO₂ emissions 10kg CO₂e
Carpool	Average Price$56 - $114	Average Duration5h 20m	CO₂ emissions 18kg CO₂e

Where are the popular stops in Luxembourg and Lyon?

Stops in Luxembourg

A
Luxembourg
3 Rue Genistre, 1623 Luxembourg, Luxembourg
B
Luxembourg Central Station
Place de la Gare 13, 1616 Luxembourg
C
Luxembourg Kirchberg
Rue Alphonse Weicker 4, 2721 Luxemburg, Luxemburg
D
Rue du Commerce
Rue du Commerce, 1351 Luxembourg, Luxembourg

Stops in Lyon

A
Perrache
Rue de Esplanade, 69002 Lyon, France
Visit page
B
Lyon Airport
Visit page
C
Lyon
8 Rue de la Paix, 69700 Givors, France
D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France
E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France
F
Les Charrières
Les Charrières, 69570 Dardilly, France
Visit page

Compare bus companies

FlixBus

3.5/511,420 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

BlaBlaCar Bus

3.5/511,150 reviews

Staff4.4

Timeliness3.6

Cleanliness4.3

Wifi2.6

FR Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about travelling from Luxembourg to Lyon by bus

What is the travel distance from Luxembourg to Lyon?
It's about 443 km (275 miles) from Luxembourg to Lyon.
What are the departure and arrival locations for buses traveling from Luxembourg to Lyon?
Buses departing from Luxembourg in Luxembourg will take you to Perrache in Lyon.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-22

$70

11-23

$86

Today

$49

11-25

$52

11-26

$55

11-27

$124

11-28

$74

11-29

$61

The cheapest trip from Luxembourg to Lyon was searched and found on Nov 24, 2025 with a price of $49

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Luxembourg to Lyon, as early as possible.

You can expect to pay from $49 to $144 for a bus ticket from Luxembourg to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $52 which is on 2025-11-25.