Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Luxembourg | Perrache | Cheapest | ||||
| Bus | Luxembourg | Perrache | Fastest | ||||
 | Bus | Luxembourg | Lyon - Perrache Bus Station | No tags | ||||
| Bus | Luxembourg | Perrache | No tags | ||||
| Bus | Luxembourg | Lyon - Perrache Bus Station | No tags |
Last refresh of the prices: Yesterday at 21:13 CET.
Compare 3 ways to travel from Luxembourg to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 5 hours 20 minutes and with fares starting at just £30, it presents an excellent value for a comfortable ride.
Where are the popular stops in Luxembourg and Lyon?
Stops in Luxembourg
- A
Luxembourg
3 Rue Genistre, 1623 Luxembourg, Luxembourg - B
Luxembourg Central Station
Place de la Gare 13, 1616 Luxembourg - C
Luxembourg Kirchberg
Rue Alphonse Weicker 4, 2721 Luxemburg, Luxemburg - D
Rue du Commerce
Rue du Commerce, 1351 Luxembourg, Luxembourg
Stops in Lyon
- ARue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
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Frequently asked questions about travelling by bus from Luxembourg to Lyon
How far is Lyon from Luxembourg by coach?
The journey from Luxembourg to Lyon by coach covers an approximate distance of 275 miles (443 km).
Is there a way to reach Lyon from Luxembourg without flying?
You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Luxembourg to Lyon was searched and found on 1 Dec 2025 with a price of £27To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Luxembourg to Lyon as early as possible.
You can expect to pay from £27 to £95 for a bus ticket from Luxembourg to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at £27, which is on 2025-12-01.
Usually BlaBlaCar Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
