Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Mesa Bus Stop | Chicago 95Th & Dan Ryan | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Mesa Bus Stop | Downtown Greyhound Station | Fastest | ||||
 | Bus | Mesa Bus Stop | 537-517 W. Jackson Blvd | No tags |
Last refresh of the prices: Yesterday at 3:59 PM MST.
Get from Mesa to Chicago
The journey takes about 1 day, 19 hours 40 minutes, and with fares starting at just ZAR 2,399, it presents an excellent value for a comfortable ride.
Bus stations and stops in Mesa and Chicago
Stops in Mesa
- A
Mesa Bus Station
1423 S Country Club , Mesa, AZ 85210, USA
Stops in Chicago
- A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA - C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Based on 88030 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at ZAR 2,482
Frequently asked questions about travelling from Mesa to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mesa to Chicago?
The cheapest bus tickets from Mesa to Chicago start from ZAR 2,399. The average price for this route is around ZAR 3,485. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mesa to Chicago?
The average bus travel time from Mesa to Chicago is 1d 19h, covering a distance of 2319 km. The quickest bus can get you there in 1d 18h and is operated by Greyhound.
Which bus companies service the Mesa to Chicago route?
Several major bus companies operate on this route with 6 buses available per day.
What are the earliest and latest departure times for the bus from Mesa to Chicago?
The earliest bus departs from Mesa to Chicago at 7:40am. And the latest bus departs at 7:55pm.
What are the CO₂ emissions for the bus trip from Mesa to Chicago?
A bus trip from Mesa to Chicago generates an estimated 57.973974999999996 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mesa to Chicago was searched and found on Aug 12, 2026 with a price of ZAR 3,167To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mesa to Chicago, as early as possible.
You can expect to pay from ZAR 3,167 to ZAR 7,677 for a bus ticket from Mesa to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at ZAR 3,167 which is on 2026-08-12.
