Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Messina Centrale | Lampugnano | Cheapest | ||||
 | Bus | Piazza della Repubblica | Milan San Donato Bus Station | Fastest | ||||
| Bus | Piazza della Repubblica | Lampugnano | No tags | ||||
| Bus | Messina Centrale | Lampugnano | No tags | ||||
| Bus | Messina Centrale | Lampugnano | No tags |
Last refresh of the prices: Yesterday at 10:20 PM CET.
Compare 2 ways to go from Messina to Milano
Among the sustainable travel choices, the carpool stands out as a good way to reach Milano. The journey takes about 13 hours 40 minutes, and with fares starting at just $106, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$62 - $374 | Average Duration21h 5m | 24kg CO₂e | ||
Carpool | Average Price$106 - $172 | Average Duration13h 40m | 41kg CO₂e |
Where are the popular stops in Messina and Milano?
Stops in Messina
- APiazza Stazione, 98122 Messina ME, Italy
- B
Piazza della Repubblica
Via Guido delle Colonne, 49, 98122 Messina ME, Italy - C
Via Giuseppe Garibaldi 263
Via Giuseppe Garibaldi 263, 98122 Messina ME, Italy - D
Porto
Capitaneria di Porto, Via Vittorio Emanuele II, 111, 98100 Messina ME, Italy
Stops in Milano
- AVia Giulio Natta, 228, 20151 Milano, Italy
- BPiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- DVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Compare bus companies
Frequently asked questions about travelling from Messina to Milano by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Messina to Milano?
The cheapest bus tickets from Messina to Milano start from $62. The average price for this route is around $171. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Messina to Milano?
The average bus travel time from Messina to Milano is 21h 5m, covering a distance of 971 km. The quickest bus can get you there in 15h 55m and is operated by Autoservizi Salemi.
Which bus companies service the Messina to Milano route?
Several major bus companies operate on this route with 22 buses available per day, including services from FlixBus, Itabus, Autoservizi Salemi.
What are the earliest and latest departure times for the bus from Messina to Milano?
The earliest bus departs from Messina to Milano at 12:50am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Messina to Milano?
A bus trip from Messina to Milano generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Messina to Milano?
According to Busbud customers, the highest-rated bus company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 459 reviews.
Which bus company has the best Wi-Fi from Messina to Milano?
Based on Busbud reviews, the bus company Autoservizi Salemi has the highest Wi-Fi rating with a score of 4.0.
Which bus company has the best on-time performance from Messina to Milano?
According to Busbud traveller reviews, the most punctual bus company on this route is Autoservizi Salemi, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Messina to Milano?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Autoservizi Salemi, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Messina to Milano was searched and found on Jan 11, 2026 with a price of $68To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Messina to Milano, as early as possible.
You can expect to pay from $68 to $308 for a bus ticket from Messina to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $68 which is on 2026-01-11.
Usually Itabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
