Bus Tickets from Milan to Syracuse

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TodayMay 25
from US$139
TomorrowMay 26
from US$114
TueMay 27
from US$83
WedMay 28
ThuMay 29
FriMay 30
SatMay 31
SunJun 1

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: May 26 at
    Departure city: Milan
    Departure location: Lampugnano bus station
    Arrival time: May 27 at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 26 at
    Departure city: Milan
    Departure location: Lampugnano bus station
    Arrival time: May 27 at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 26 at
    Departure city: Milan
    Departure location: Milan (San Donato M3)
    Arrival time: May 27 at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 26 at
    Departure city: Milan
    Departure location: Milan (Assago M2)
    Arrival time: May 27 at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 26 at
    Departure city: Milan
    Departure location: Via Luigi Cadorna
    Arrival time: May 27 at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 12:31 PM CEST.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Milan to Syracuse

Bus
Average PriceUS$59 - US$209Average Duration1d 3h
27kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average PriceUS$67 - US$67Average Duration15h 40m
45kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Milan to Syracuse

Among the sustainable travel choices, the carpool stands out as a good way to reach Syracuse. The journey takes about 15 hours 40 minutes, and with fares starting at just US$67, it presents an excellent value for a comfortable ride.

1carpool per day
15h 40mAverage Duration
US$67Cheapest ticket
45kgCO₂ emissions

Bus Milan to Syracuse: Trip Overview

Average Ticket PriceUS$105
Average Bus Trip Duration1d 3h
Number of daily buses6
Earliest bus departure12:55pm
Distance1099 km
Latest bus departure9:30pm

Milan to Syracuse Bus

With Busbud, comparing and booking tickets for a bus from Milan to Syracuse is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Milan to Syracuse.

Discover how much the bus trip from Milan to Syracuse will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Milan - Syracuse

  1. How long is the trip from Milan to Syracuse by bus?

    The bus ride from Milan to Syracuse takes 1d 3h, on average. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 20h 40m.

  2. What is the travel distance from Milan to Syracuse?

    Milan and Syracuse are 1064 km (660 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Milan to Syracuse?

    Buses departing from Lampugnano in Milan will take you to Fermata dell'autobus Siracusa in Syracuse.

  4. What is the cheapest way to get from Milan to Syracuse?

    If you're on a budget, consider traveling by bus to Syracuse from Milan; it tends to be more affordable. The ticket price for this bus starts at US$59, making this your best choice for this trip.

  5. How much does the bus ticket cost from Milan to Syracuse?

    The bus from Milan to Syracuse will cost you US$105, on average.

  6. Is there an overnight bus from Milan to Syracuse?

    Yes! If you're heading from Milan to Syracuse, you'll find buses departing until 9:30pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-23
US$98
05-24
No data
Today
US$131
05-26
US$107
05-27
US$78
05-28
No data
05-29
No data
05-30
No data
busbud logoThe cheapest trip from Milan to Syracuse was searched and found on May 27, 2025 with a price of US$78

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milan to Syracuse, as early as possible.

You can expect to pay from US$78 to US$208 for a bus ticket from Milan to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at US$78 which is on 2025-05-27.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Milan to Syracuse.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Milan to Syracuse.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Milan to Syracuse will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Milan to Syracuse, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Milan by bus?

Bus from Milan to Syracuse

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