Bus Tickets from Rome to Syracuse

Find affordable bus tickets from Rome to Syracuse with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TomorrowMay 7
ThuMay 8
from US$85
FriMay 9
SatMay 10
SunMay 11
MonMay 12
TueMay 13
WedMay 14

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 8 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: May 8 at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 8 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: May 9 at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Rome
    Departure location: Rome Fiumicino Airport
    Arrival time: May 9 at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: May 9 at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Rome
    Departure location: Aeroporto Ciampino Airport (CIA)
    Arrival time: May 9 at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

Last refresh of the prices: Today at 2:07 PM CEST.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 3 ways to go from Rome to Syracuse

Bus
Average PriceUS$50 - US$214Average Duration19h 25m
15kg CO₂e5 out of 5 stars
Train
Average PriceUS$75 - US$331Average Duration11h 2m
14kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average PriceUS$46 - US$82Average Duration10h 10m
25kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends carpooling from Rome to Syracuse

Among the sustainable travel choices, the carpool stands out as a good way to reach Syracuse. The journey takes about 10 hours 10 minutes, and with fares starting at just US$46, it presents an excellent value for a comfortable ride.

4carpool per day
10h 10mAverage Duration
US$46Cheapest ticket
25kgCO₂ emissions

Bus Rome to Syracuse: Trip Overview

Average Ticket PriceUS$88
Average Bus Trip Duration19h 25m
Number of daily buses3
Earliest bus departure1:15am
Distance588 km
Latest bus departure11:45pm

Rome to Syracuse Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Rome to Syracuse.

Bus service from Rome to Syracuse will be provided by the most trusted bus companies.

Discover how much the bus trip from Rome to Syracuse will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Rome - Syracuse

  1. How long is the bus trip from Rome to Syracuse?

    The typical travel time from Rome to Syracuse by bus is around 19h 25m. For the shortest travel time, select the fastest bus available, which will take you to Syracuse in about 13h 20m.

  2. How far is Rome from Syracuse?

    It's about 588 km (365 miles) from Rome to Syracuse.

  3. What are the departure and arrival locations for buses traveling from Rome to Syracuse?

    Buses traveling this route start their trip at Rome Tiburtina Bus Station, in Rome, and end it at Fermata dell'autobus Siracusa, in Syracuse.

  4. What is the cheapest way to travel from Rome to Syracuse?

    The least expensive way to go from Rome to Syracuse would be going by bus. Starting at US$50, this bus is the most cost-effective option for your journey.

  5. How much does it cost to take the bus from Rome to Syracuse?

    Taking the bus from Rome to Syracuse costs on average US$88.

  6. Can I take an overnight bus from Rome to Syracuse?

    Yes! Catch buses leaving from Rome until 11:45pm and reaching Syracuse on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-04
US$114
05-05
US$86
Today
US$52
05-07
No data
05-08
US$79
05-09
US$63
05-10
US$46
05-11
US$76
busbud logoThe cheapest trip from Rome to Syracuse was searched and found on May 10, 2025 with a price of US$46

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Syracuse, as early as possible.

You can expect to pay from US$46 to US$147 for a bus ticket from Rome to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at US$46 which is on 2025-05-10.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Rome to Syracuse but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Rome to Syracuse, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Rome to Syracuse will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Rome to Syracuse, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Rome by bus?

Bus from Rome to Syracuse

You can also go to Syracuse by train

Train from Rome to Syracuse

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Rome

Buses Leaving from Rome

Buses Going to Rome

Popular Buses Connecting Syracuse

Buses Leaving from Syracuse

Buses Going to Syracuse