Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | Lafayette Bus Stop | Cheapest | ||||
| Bus | Gateway Station | Lafayette Bus Stop | Fastest | ||||
| Bus | Gateway Station | Lafayette Bus Stop | No tags |
Last refresh of the prices: Yesterday at 7:13 PM CST.
Compare 2 ways to go from St. Louis to Lafayette
Among the sustainable travel choices, the bus stands out as a good way to reach Lafayette. The journey takes about 9 hours 5 minutes, and with fares starting at just $59, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Lafayette?
Stops in Lafayette
- A
CityBus Center
N 3rd St & North St (Corner), Lafayette, IN 47901
Compare bus companies
Frequently asked questions about travelling from St. Louis to Lafayette, IN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from St. Louis to Lafayette?
The cheapest bus tickets from St. Louis to Lafayette start from $59. The average price for this route is around $90. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Lafayette?
The average bus travel time from St. Louis to Lafayette is 9h 5m, covering a distance of 348 km. The quickest bus can get you there in 6h 20m and is operated by Greyhound.
Which bus companies service the St. Louis to Lafayette route?
What are the earliest and latest departure times for the bus from St. Louis to Lafayette?
The earliest bus departs from St. Louis to Lafayette at 2:00am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from St. Louis to Lafayette?
A bus trip from St. Louis to Lafayette generates an estimated 9 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from St. Louis to Lafayette?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from St. Louis to Lafayette?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from St. Louis to Lafayette?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to Lafayette?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Lafayette, IN was searched and found on Dec 19, 2025 with a price of $62To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Lafayette, IN, as early as possible.
You can expect to pay from $62 to $70 for a bus ticket from St. Louis to Lafayette, IN based on the last 2 days. You can expect to find the cheapest price for the trip at $62 which is on 2025-12-19.
What's the cheapest way to go from St. Louis to Lafayette, IN?
The bus is the cheapest travel choice for this destination
