Bus Tickets from St. Louis to Lexington, KY

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TodaySep 2
TomorrowSep 3
from US$61
ThuSep 4
from US$56
FriSep 5
SatSep 6
from US$59
SunSep 7
MonSep 8
from US$54
TueSep 9

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: September 3 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: September 3 at
    Destination city: Lexington
    Destination location: WJW Investments Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: September 3 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: September 3 at
    Destination city: Lexington
    Destination location: WJW Investments Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: September 3 at
    Destination city: Lexington
    Destination location: WJW Investments Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus St. Louis to Lexington, KY: Trip Overview

Average Ticket PriceUS$63
Average Bus Trip Duration8h 45m
Number of daily buses2
Earliest bus departure2:00am
Distance503 km
Latest bus departure1:55pm

St. Louis to Lexington Bus

Busbud helps you find a bus from St. Louis to Lexington. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from St. Louis to Lexington from the most reliable bus companies operating this trip.

Discover how much the bus trip from St. Louis to Lexington will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip St. Louis - Lexington, KY

  1. What is the travel distance from St. Louis to Lexington?

    It's about 504 km (313 miles) from St. Louis to Lexington.

  2. What are the departure and arrival locations for buses traveling from St. Louis to Lexington?

    Buses departing from Gateway Station in St. Louis will take you to WJW Investments Bus Stop in Lexington.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-31
No data
09-01
No data
Today
No data
09-03
US$54
09-04
US$49
09-05
No data
09-06
US$51
09-07
No data
busbud logoThe cheapest trip from St. Louis to Lexington, KY was searched and found on Sep 4, 2025 with a price of US$49

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Lexington, KY, as early as possible.

You can expect to pay from US$49 to US$64 for a bus ticket from St. Louis to Lexington, KY based on the last 2 days. You can expect to find the cheapest price for the trip at US$49 which is on 2025-09-04.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between St. Louis and Lexington!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from St. Louis to Lexington, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from St. Louis to Lexington will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St. Louis to Lexington.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to St. Louis by bus?

Bus from Lexington, KY to St. Louis

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