Bus Tickets from Talcahuano to Santiago, CL

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MonAug 4
from US$15
TueAug 5
from US$14
WedAug 6
from US$14
ThuAug 7
from US$14
FriAug 8
from US$15
SatAug 9
from US$15
SunAug 10
MonAug 11

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 5 at
    Departure city: Talcahuano
    Departure location: Talcahuano
    Arrival time: August 5 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 5 at
    Departure city: Talcahuano
    Departure location: Talcahuano
    Arrival time: August 5 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: August 5 at
    Departure city: Talcahuano
    Departure location: Talcahuano
    Arrival time: August 5 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: August 5 at
    Departure city: Talcahuano
    Departure location: Talcahuano
    Arrival time: August 6 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: August 5 at
    Departure city: Talcahuano
    Departure location: Talcahuano
    Arrival time: August 5 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:

Last refresh of the prices: Last Tuesday at 9:56 AM -04.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Talcahuano to Santiago, CL: Trip Overview

Average Ticket PriceUS$20
Average Bus Trip Duration5h 19m
Number of daily buses6
Earliest bus departure8:15am
Distance426 km
Latest bus departure11:15pm

Talcahuano to Santiago Bus

With Busbud, comparing and booking tickets for a bus from Talcahuano to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Talcahuano to Santiago from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Santiago from Talcahuano, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Talcahuano - Santiago, CL

  1. How far is Talcahuano from Santiago?

    The distance between Talcahuano and Santiago is approximately 435 km (270 miles).

  2. What are the departure and arrival locations for buses traveling from Talcahuano to Santiago?

    Buses departing from Alto Horno, 777 in Talcahuano will take you to Terminal Sur in Santiago.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-31
US$13
08-01
US$14
Today
US$14
08-03
US$14
08-04
US$14
08-05
US$13
08-06
US$13
08-07
US$13
busbud logoThe cheapest trip from Talcahuano to Santiago, CL was searched and found on Aug 7, 2025 with a price of US$13

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Talcahuano to Santiago, CL, as early as possible.

You can expect to pay from US$13 to US$32 for a bus ticket from Talcahuano to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at US$13 which is on 2025-08-07.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Talcahuano to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Talcahuano to Santiago, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Talcahuano to Santiago.

Tune out to the fine sounds of your best music playlist on your bus trip from Talcahuano to Santiago while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Talcahuano by bus?

Bus from Talcahuano to Santiago, CL

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