Train from Greenville, SC to Pittsburgh: Tickets & Schedules

Previously seen trips

Next departures for Greenville to Pittsburgh on December 14
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Greenville Station
Union StationNo tags
AmtrakTrain
Greenville Station
Union StationNo tags
AmtrakTrain
Greenville Station
Union StationNo tags
AmtrakTrain
Greenville Station
Union StationNo tags
AmtrakTrain
Greenville Station
Union StationNo tags

Compare 2 ways to go from Greenville to Pittsburgh

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Pittsburgh. The journey takes about 18 hours, and with fares starting at just $159, it presents an excellent value for a comfortable ride.

3bus per day
18hAverage Duration
657 kmDistance
16kgCO₂ emissions
Average Price$159 - $598Average Duration18h
16kg CO₂e
Average Price$242 - $1,572Average Duration21h 17m
60kg CO₂e

Frequently asked questions about travelling from Greenville, SC to Pittsburgh by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Greenville to Pittsburgh?

    The cheapest train tickets from Greenville to Pittsburgh start at $242. The average price for this train route is around $375. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.

  2. How long is the train ride from Greenville to Pittsburgh?

    The average train trip from Greenville to Pittsburgh takes 21h 17m and covers 657 km. The quickest train gets you there in 21h 17m and is operated by Amtrak.

  3. Which train operators serve the Greenville to Pittsburgh route?

    Several major train operators serve this route, with 1 trains available per day.

  4. What are the earliest and latest departure times for the train from Greenville to Pittsburgh?

    The earliest train from Greenville to Pittsburgh departs at 2:23am. The latest train departs at 2:23am.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12-12
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12-13
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Today
$341
12-15
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12-16
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12-17
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12-18
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12-19
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busbud logoThe cheapest trip from Greenville, SC to Pittsburgh was searched and found on Dec 14, 2025 with a price of $341

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville, SC to Pittsburgh, as early as possible.

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