Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Greenville Station | Union Station | No tags | ||||
| Train | Greenville Station | Union Station | No tags | ||||
| Train | Greenville Station | Union Station | No tags | ||||
| Train | Greenville Station | Union Station | No tags | ||||
| Train | Greenville Station | Union Station | No tags |
Compare 2 ways to go from Greenville to Pittsburgh
Among the sustainable travel choices, the bus stands out as the good way to reach Pittsburgh. The journey takes about 18 hours and with fares starting at just $113, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5644 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $171
Frequently asked questions about traveling from Greenville, SC to Pittsburgh by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Greenville to Pittsburgh?
The cheapest train tickets from Greenville to Pittsburgh start from $171. The average price for this train route is around $266. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Greenville to Pittsburgh?
The average train ride duration from Greenville to Pittsburgh is 21h 17m, covering a distance of 408 miles (657 km). The quickest train can get you there in 21h 17m and is operated by Amtrak.
Which train operators service the Greenville to Pittsburgh route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Greenville to Pittsburgh?
The earliest train departs from Greenville to Pittsburgh at 2:23am. And the latest train departs at 2:23am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Pittsburgh was searched and found on Dec 14, 2025 with a price of $241To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville, SC to Pittsburgh, as early as possible.
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