How much is the bus ticket from Greenville to Pittsburgh?

The cheapest bus tickets from Greenville to Pittsburgh start from $126. The average price for this route is around $218. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Greenville to Pittsburgh?

The average bus travel time from Greenville to Pittsburgh is 18h 25m, covering a distance of 657 km. The quickest bus can get you there in 17h 5m and is operated by FlixBus .

Which bus companies service the Greenville to Pittsburgh route?

Several major bus companies operate on this route with 3 buses available per day, including services from FlixBus , Greyhound .

What are the earliest and latest departure times for the bus from Greenville to Pittsburgh?

The earliest bus departs from Greenville to Pittsburgh at 10:50am. And the latest bus departs at 10:00pm.

What are the CO₂ emissions for the bus trip from Greenville to Pittsburgh?

A bus trip from Greenville to Pittsburgh generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Greenville to Pittsburgh?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11828 reviews.

Which bus company has the best Wi-Fi from Greenville to Pittsburgh?

Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

Which bus company has the best on-time performance from Greenville to Pittsburgh?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Greenville to Pittsburgh?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Greenville to Pittsburgh from $122 | Refundable Tickets

Next bus departures

Next departures for Greenville to Pittsburgh on January 12
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	18h	10:15am	Pittsburgh Intermodal Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	19h 50m	5:50pm	Pittsburgh Intermodal Station	No tags

Next departures for Greenville to Pittsburgh on January 13
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	10:50am	1116 Woodruff Rd	19h 40m	6:30am	Pittsburgh Intermodal Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	1:20pm	1116 Woodruff Rd	1d 4h	5:40pm	Pittsburgh Intermodal Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	19h 50m	5:50pm	Pittsburgh Intermodal Station	No tags

Next departures for Greenville to Pittsburgh on January 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	1:20pm	1116 Woodruff Rd	1d 4h	5:40pm	Pittsburgh Intermodal Station	Cheapest
	Bus	10:50am	1116 Woodruff Rd	19h 40m	6:30am	Pittsburgh Intermodal Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	19h 50m	5:50pm	Pittsburgh Intermodal Station	No tags

Next departures for Greenville to Pittsburgh on January 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	19h 50m	5:50pm	Pittsburgh Intermodal Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	18h	10:15am	Pittsburgh Intermodal Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15pm	1116 Woodruff Rd	18h 15m	6:30am	Pittsburgh Intermodal Station	No tags

Next departures for Greenville to Pittsburgh on January 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	19h 50m	5:50pm	Pittsburgh Intermodal Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	18h	10:15am	Pittsburgh Intermodal Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15pm	1116 Woodruff Rd	18h 15m	6:30am	Pittsburgh Intermodal Station	No tags

Next departures for Greenville to Pittsburgh on January 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	19h 50m	5:50pm	Pittsburgh Intermodal Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	18h	10:15am	Pittsburgh Intermodal Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15pm	1116 Woodruff Rd	18h 15m	6:30am	Pittsburgh Intermodal Station	No tags

Next departures for Greenville to Pittsburgh on January 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	12:15pm	1116 Woodruff Rd	18h 15m	6:30am	Pittsburgh Intermodal Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	4:15pm	1116 Woodruff Rd	18h	10:15am	Pittsburgh Intermodal Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	10:00pm	1116 Woodruff Rd	19h 50m	5:50pm	Pittsburgh Intermodal Station	No tags

Last refresh of the prices: Yesterday at 4:24 PM EST.

Compare 2 ways to go from Greenville to Pittsburgh

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Pittsburgh. The journey takes about 18 hours 25 minutes, and with fares starting at just $126, it presents an excellent value for a comfortable ride.

3bus per day

18h 25mAverage Duration

657 kmDistance

16kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$126 - $393	Average Duration18h 25m	CO₂ emissions 16kg CO₂e
Train	Average Price$228 - $1,869	Average Duration21h 17m	CO₂ emissions 60kg CO₂e

Where are the popular stops in Greenville and Pittsburgh?

Stops in Greenville

A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611
Map
B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Map

Stops in Pittsburgh

A
Intermodal Station
55 11th St, Pittsburgh, PA 15222, USA
Visit page Map
B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
Map

Compare bus companies

FlixBus

3.5/512,012 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Greyhound

3.5/587,495 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Greenville, SC to Pittsburgh by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Greenville to Pittsburgh?
The cheapest bus tickets from Greenville to Pittsburgh start from $126. The average price for this route is around $218. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Pittsburgh?
The average bus travel time from Greenville to Pittsburgh is 18h 25m, covering a distance of 657 km. The quickest bus can get you there in 17h 5m and is operated by FlixBus.
Which bus companies service the Greenville to Pittsburgh route?
Several major bus companies operate on this route with 3 buses available per day, including services from FlixBus, Greyhound.
What are the earliest and latest departure times for the bus from Greenville to Pittsburgh?
The earliest bus departs from Greenville to Pittsburgh at 10:50am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Pittsburgh?
A bus trip from Greenville to Pittsburgh generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Greenville to Pittsburgh?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11828 reviews.
Which bus company has the best Wi-Fi from Greenville to Pittsburgh?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Greenville to Pittsburgh?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Pittsburgh?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01-10

No data

01-11

No data

Today

$211

01-13

$193

01-14

$165

01-15

No data

01-16

No data

01-17

No data

The cheapest trip from Greenville, SC to Pittsburgh was searched and found on Jan 14, 2026 with a price of $165

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Pittsburgh, as early as possible.

You can expect to pay from $165 to $211 for a bus ticket from Greenville, SC to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at $165 which is on 2026-01-14.