Train tickets from Chicago to San Diego, CA, US

Previously seen trips

Next departures for Chicago to San Diego on November 20
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Chicago (Union Station), IL
Santa Fe DepotNo tags
AmtrakTrain
Chicago (Union Station), IL
Old Town San DiegoNo tags
AmtrakTrain
Chicago (Union Station), IL
Santa Fe DepotNo tags
AmtrakTrain
Chicago (Union Station), IL
Old Town San DiegoNo tags
AmtrakTrain
Chicago (Union Station), IL
Santa Fe DepotNo tags

Compare 2 ways to go from Chicago to San Diego

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach San Diego. The journey takes about 2 days, 7 hours 45 minutes, and with fares starting at just $170, it presents an excellent value for a comfortable ride.

21bus per day
2d 7hAverage Duration
2782 kmDistance
70kgCO₂ emissions
Average Price$170 - $837Average Duration2d 7h
70kg CO₂e
Average Price$267 - $2,227Average Duration2d
254kg CO₂e

Frequently asked questions about travelling from Chicago to San Diego, CA, US by train

  1. How much does a cheap train ticket from Chicago to San Diego cost?

    The average train ticket price from Chicago to San Diego is $372. The best way to find cheap train tickets from Chicago to San Diego is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the trip from Chicago to San Diego?

    A train trip between Chicago and San Diego is around 2d , although the fastest train will take about 2d . This is the time it takes to travel the 2788 km that separates the two cities.

  3. How many daily trains are there between Chicago and San Diego?

    The number of trains from Chicago to San Diego can differ depending on the day of the week. On average, there are 3. Some trains are direct while others include transferring trains. Simplify your train trip from Chicago to San Diego by comparing and selecting the train that fits your travel style and budget on Busbud.

  4. Which train companies travel from Chicago to San Diego?

    When taking the train from Chicago to San Diego, you can travel comfortably and safely with Amtrak.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-17
$257
11-18
$350
Today
$411
11-20
$350
11-21
$411
11-22
$350
11-23
$350
11-24
No data
busbud logoThe cheapest trip from Chicago to San Diego, CA, US was searched and found on Nov 17, 2025 with a price of $257

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Chicago to San Diego, CA, US, as early as possible.

You can expect to pay from $257 to $2,150 for a train ticket from Chicago to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $350 which is on 2025-11-20.

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