Train from Detroit, MI to Greenville, SC: Tickets & Schedules

Previously seen trips

Next departures for Detroit to Greenville on November 26
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Amtrak Station
Greenville StationNo tags
AmtrakTrain
Amtrak Station
Greenville StationNo tags
AmtrakTrain
Amtrak Station
Greenville StationNo tags
AmtrakTrain
Amtrak Station
Greenville StationNo tags
AmtrakTrain
Amtrak Station
Greenville StationNo tags

Compare 2 ways to go from Detroit to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 25 minutes, and with fares starting at just $133, it presents an excellent value for a comfortable ride.

3bus per day
1d Average Duration
837 kmDistance
21kgCO₂ emissions
Average Price$133 - $663Average Duration1d
21kg CO₂e
Average Price$367 - $883Average Duration1d 19h
76kg CO₂e

Frequently asked questions about travelling from Detroit, MI to Greenville, SC by train

  1. How much does a cheap train ticket from Detroit to Greenville cost?

    The average train ticket price from Detroit to Greenville is $525. The best way to find cheap train tickets from Detroit to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the trip from Detroit to Greenville?

    A train trip between Detroit and Greenville is around 1d 19h, although the fastest train will take about 1d 19h. This is the time it takes to travel the 835 km that separates the two cities.

  3. How many daily trains are there between Detroit and Greenville?

    The number of trains from Detroit to Greenville can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Detroit to Greenville by comparing and selecting the train that fits your travel style and budget on Busbud.

  4. Which train companies travel from Detroit to Greenville?

    When taking the train from Detroit to Greenville, you can travel comfortably and safely with Amtrak.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-24
No data
11-25
$571
Today
No data
11-27
No data
11-28
No data
11-29
$689
11-30
No data
12-01
No data
busbud logoThe cheapest trip from Detroit, MI to Greenville, SC was searched and found on Nov 25, 2025 with a price of $571

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Detroit, MI to Greenville, SC, as early as possible.

You can expect to pay from $571 to $2,942 for a train ticket from Detroit, MI to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $689 which is on 2025-11-29.

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