How much does a train ticket from Detroit to Greenville cost?

The average train ticket price from Detroit to Greenville is $364. The best way to find train tickets from Detroit to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the train trip from Detroit to Greenville?

A train trip between Detroit and Greenville is around 1d 19h, although the fastest train will take about 1d 19h. This is the time it takes to travel the 518 miles that separates the two cities.

How many daily trains are there between Detroit and Greenville?

The number of trains from Detroit to Greenville can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Detroit to Greenville by comparing and selecting the train that fits you travel style and budget on Busbud.

Which train companies travel from Detroit to Greenville?

When taking the train from Detroit to Greenville, you can travel comfortably and safely with Amtrak.

Train Detroit to Greenville from $252 | Refundable Tickets

Previously seen trips

Next departures for Detroit to Greenville on November 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags
Train	9:35am	Amtrak Station	1d 19h	5:24am	Greenville Station	No tags

Compare 2 ways to go from Detroit to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 1 day, 25 minutes and with fares starting at just $92, it presents an excellent value for a comfortable ride.

3bus per day

1d Average Duration

519 milesDistance

21kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$92 - $459	Average Duration1d	CO₂ emissions 21kg CO₂e
Train	Average Price$254 - $611	Average Duration1d 19h	CO₂ emissions 76kg CO₂e

Train Companies

Amtrak

4/55,607 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5607 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $254

Train and bus companies in US:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from Detroit, MI to Greenville, SC by train

How much does a train ticket from Detroit to Greenville cost?
How long is the train trip from Detroit to Greenville?
How many daily trains are there between Detroit and Greenville?
Which train companies travel from Detroit to Greenville?

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/24

No data

11/25

$395

Today

No data

11/27

No data

11/28

No data

11/29

$477

11/30

No data

12/01

No data

The cheapest trip from Detroit, MI to Greenville, SC was searched and found on Nov 25, 2025 with a price of $395

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Detroit, MI to Greenville, SC, as early as possible.

You can expect to pay from $395 to $2,037 for a train ticket from Detroit, MI to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $477 which is on 2025-11-29.