Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Amtrak Station | Chicago (Union Station), IL | CheapestFastest | ||||
| Train | Amtrak Station | Chicago (Union Station), IL | No tags |
Last refresh of the prices: Yesterday at 10:29 PM EST.
Compare 2 ways to go from Syracuse to Chicago
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 5 hours, and with fares starting at just $81, it presents an excellent value for a comfortable ride.
Train companies
Based on 5594 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $86
Where are the popular train stations and stops in Syracuse, US and Chicago?
Frequently asked questions about travelling from Syracuse, US to Chicago by train
How much does a cheap train ticket from Syracuse to Chicago cost?
The average train ticket price from Syracuse to Chicago is $214. The best way to find cheap train tickets from Syracuse to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the trip from Syracuse to Chicago?
A train trip between Syracuse and Chicago is around 13h 7m, although the fastest train will take about 13h 7m. This is the time it takes to travel the 954 km that separates the two cities.
How many daily trains are there between Syracuse and Chicago?
The number of trains from Syracuse to Chicago can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Syracuse to Chicago by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Syracuse to Chicago?
When taking the train from Syracuse to Chicago, you can travel comfortably and safely with Amtrak.
What are the departure and arrival stations for a train from Syracuse to Chicago?
Trains travelling between Syracuse and Chicago leave from Regional Transportation Center or Syracuse Airport and arrive at Union Station.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Chicago was searched and found on Nov 19, 2025 with a price of $245To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Syracuse, US to Chicago, as early as possible.
You can expect to pay from $245 to $2,509 for a train ticket from Syracuse, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $245 which is on 2025-11-23.
