Bus from Charleston, SC, US to Indianapolis: Tickets & Timetables

Previously seen journeys

Next departures from Charleston to Indianapolis on 4 January
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Downtown Transit CenterNo tags
FlixBus + Greyhound
Bus
4565 Gaynor Ave, North Charleston
Indianapolis Bus StationNo tags
FlixBus + Greyhound
Bus
4565 Gaynor Ave, North Charleston
Downtown Transit CenterNo tags
Greyhound + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Indianapolis Bus StationNo tags
Greyhound + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Downtown Transit CenterNo tags

Compare 2 ways to travel from Charleston to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 1 day, 8 hours 35 minutes and with fares starting at just £103, it presents an excellent value for a comfortable ride.

2bus per day
1d 8hAverage duration
585 milesDistance
24kgCO₂ emissions
Average price£103 - £264Average duration1d 8h
24kg CO₂e
Average price£282 - £420Average duration1d 7h
86kg CO₂e

Frequently asked questions about travelling by bus from Charleston, SC, US to Indianapolis

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from Charleston to Indianapolis?

    The cheapest coach tickets from Charleston to Indianapolis start from £103. The average price for this route is around £146. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from Charleston to Indianapolis?

    The average bus journey time from Charleston to Indianapolis is 1d 8h, covering a distance of 585 miles. The fastest bus can take you there in 1d and is operated by Greyhound.

  3. Which bus companies service the Charleston to Indianapolis route?

    Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Charleston to Indianapolis?

    The earliest bus departs from Charleston to Indianapolis at 11:15. And the latest bus departs at 11:15.

  5. What are the CO₂ emissions for the bus trip from Charleston to Indianapolis?

    A bus journey from Charleston to Indianapolis produces an estimated 24 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best bus company from Charleston to Indianapolis?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.

  7. Which company has the best Wi-Fi from Charleston to Indianapolis?

    Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company offers the most punctual service from Charleston to Indianapolis?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Charleston to Indianapolis?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
02/01
£166
03/01
No data
Today
£200
05/01
No data
06/01
No data
07/01
£131
08/01
No data
09/01
£140
busbud logoThe cheapest trip from Charleston, SC, US to Indianapolis was searched and found on 7 Jan 2026 with a price of £131

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Indianapolis as early as possible.

You can expect to pay from £131 to £200 for a bus ticket from Charleston, SC, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at £131, which is on 2026-01-07.

What's the cheapest way to go from Charleston, SC, US to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

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