Find coaches from Harrisburg to Durham (NC), US

Find affordable coach tickets from Harrisburg to Durham (NC), US with flexible options. Book your journey now

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Sat7 Jun
Sun8 Jun
Mon9 Jun
from US$78
Tue10 Jun
Wed11 Jun
from US$110
Thu12 Jun
Fri13 Jun
Sat14 Jun

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 9 June at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: 9 June at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 9 June at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: 9 June at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 9 June at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: 10 June at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 9 June at
    Departure city: Harrisburg
    Departure location: Harrisburg
    Arrival time: 10 June at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 9 June at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: 10 June at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Compare 2 ways to travel from Harrisburg to Durham

Average priceUS$78 - US$147Average duration15h 15m
13kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average priceUS$148 - US$265Average duration12h 6m
46kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Harrisburg to Durham

Among the sustainable travel choices, the train stands out as a good way to reach Durham. The journey takes about 12 hours 6 minutes and with fares starting at just US$148, it presents an excellent value for a comfortable ride.

1train per day
12h 6mAverage duration
US$148Cheapest ticket
46kgCO₂ emissions

Bus Harrisburg to Durham: Trip Overview

Average ticket priceUS$102
Average bus trip duration15h 15m
Number of daily buses6
Earliest bus departure03:05
Distance314 miles
Latest bus departure21:10

Harrisburg to Durham Bus

Busbud helps you find a bus from Harrisburg to Durham. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Harrisburg to Durham will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Durham from Harrisburg, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Harrisburg - Durham (NC), US

  1. How much does the Harrisburg Durham coach trip cost?

    The price for a coach ticket from Harrisburg to Durham starts at US$78, though the average is US$102. These prices can change depending on factors like the date, the class and the coach company you choose. Compare the prices and amenities offered by each company on Busbud and find the best deals and offers.

  2. How long is the coach ride from Harrisburg to Durham?

    The average duration for a trip from Harrisburg to Durham by coach is around 15h 15m. The quickest coach journey typically takes 10h 55m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. At what time is the first coach from Harrisburg to Durham?

    The first departure to Durham is at 03:05. Keep in mind that departure times might change on weekends and holidays.

  4. How far is Durham from Harrisburg by coach?

    The distance between Harrisburg and Durham by coach is approximately 315 miles (508 km).

  5. What is the best way to go from Harrisburg to Durham without flying?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
03/06
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Today
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09/06
US$71
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busbud logoThe cheapest trip from Harrisburg to Durham was searched and found on 9 Jun 2025 with a price of US$71

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Durham as early as possible.

You can expect to pay from US$71 to US$98 for a bus ticket from Harrisburg to Durham based on the last 2 days. You can expect to find the cheapest price for the trip at US$71, which is on 2025-06-09.

Usually FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Harrisburg and Durham!

Much more than a mere vehicle taking you from Harrisburg to Durham, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Harrisburg to Durham.

Tune out to the fine sounds of your best music playlist on your bus trip from Harrisburg to Durham while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Harrisburg to Durham?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Harrisburg by bus?

Bus from Harrisburg to Durham

You can also go to Durham by train

Train from Harrisburg to Durham

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

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