Find coaches from Indianapolis to Panama City, US

Next departures

Next departures from Indianapolis to Panama City on 8 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Indianapolis Bus Station
Panama City Beach StationCheapest
FlixBus + Greyhound Lines, Inc.
Downtown Transit Center
Panama City Beach StationFastest

Last refresh of the prices: Yesterday at 15:32 EDT.

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Bus Indianapolis to Panama City, US: Trip Overview

Average ticket priceUS$79
Average bus trip duration23h 10m
Number of daily buses5
Earliest bus departure03:40
Distance661 miles
Latest bus departure23:30

Indianapolis to Panama City Bus

Busbud helps you find a bus from Indianapolis to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Indianapolis to Panama City from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Panama City from Indianapolis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Indianapolis - Panama City, US

  1. How far is Panama City from Indianapolis by coach?

    The distance between Indianapolis and Panama City by coach is approximately 664 miles (1071 km).

  2. What is the best way to go from Indianapolis to Panama City without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/10
No data
07/10
US$70
Today
US$159
09/10
No data
10/10
US$97
11/10
No data
12/10
No data
13/10
US$103
busbud logoThe cheapest trip from Indianapolis to Panama City, US was searched and found on 7 Oct 2025 with a price of US$70

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Panama City, US as early as possible.

You can expect to pay from US$70 to US$220 for a bus ticket from Indianapolis to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$97, which is on 2025-10-10.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Indianapolis and Panama City!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Indianapolis to Panama City, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Indianapolis to Panama City.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Indianapolis to Panama City.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Indianapolis by bus?

Bus from Panama City, US to Indianapolis

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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