Find coaches from Knoxville, TN to Philadelphia, PA

Next departures

Next departures from Knoxville to Philadelphia on 13 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Knoxville Bus Station
Philadelphia, 199 Spring Garden StCheapest
Greyhound Lines, Inc.
Knoxville Bus Station
199 Spring Garden St.Fastest
Greyhound Lines, Inc. + FlixBus
Knoxville Bus Station
Cherry Hill MallNo tags
Greyhound Lines, Inc.
Knoxville Bus Station
Schuylkill & WalnutNo tags
Greyhound Lines, Inc. + FlixBus
Knoxville Bus Station
Frazer - 56-40 Matthews RdNo tags

Last refresh of the prices: Last Monday at 10:30 EDT.

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Bus Knoxville, TN to Philadelphia, PA: Trip Overview

Average ticket priceUS$95
Average bus trip duration20h 45m
Number of daily buses6
Earliest bus departure22:50
Distance548 miles

Knoxville to Philadelphia Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Philadelphia.

We make sure you can find a bus service from Knoxville to Philadelphia from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Knoxville to Philadelphia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Knoxville, TN - Philadelphia, PA

  1. What's the distance between Knoxville and Philadelphia by coach?

    The distance between Knoxville and Philadelphia by coach is approximately 551 miles (888 km).

  2. How can I travel from Knoxville to Philadelphia avoiding air travel?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/10
No data
11/10
No data
Today
US$67
13/10
US$101
14/10
No data
15/10
US$87
16/10
No data
17/10
No data
busbud logoThe cheapest trip from Knoxville, TN to Philadelphia, PA was searched and found on 12 Oct 2025 with a price of US$67

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Philadelphia, PA as early as possible.

You can expect to pay from US$67 to US$101 for a bus ticket from Knoxville, TN to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at US$87, which is on 2025-10-15.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Philadelphia but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Knoxville to Philadelphia, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Knoxville to Philadelphia that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Knoxville to Philadelphia, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Knoxville, TN by bus?

Bus from Philadelphia, PA to Knoxville, TN

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