Find coaches from Mobile to Knoxville (TN)

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Today24 May
Tomorrow25 May
from US$115
Mon26 May
Tue27 May
Wed28 May
Thu29 May
Fri30 May
Sat31 May

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 25 May at
    Departure city: Mobile
    Departure location: Greyhound Station
    Arrival time: 25 May at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Mobile to Knoxville: Trip Overview

Average ticket priceUS$101
Average bus trip duration13h 35m
Number of daily buses1
Earliest bus departure07:30
Distance441 miles

Mobile to Knoxville Bus

Busbud helps you find a bus from Mobile to Knoxville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Mobile to Knoxville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Knoxville from Mobile, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Mobile - Knoxville (TN)

  1. What is the cheapest way to go from Mobile to Knoxville?

    Coach ticket prices from Mobile to Knoxville can start as low as US$84, though the average price for this trip is US$101. The cost of tickets can fluctuate based on factors like the time of day, the company, and the class you choose. To get accurate and up-to-date pricing information, check out all your options on our search tool.

  2. How long does it take to travel from Mobile to Knoxville by bus?

    The coach journey between Mobile and Knoxville lasts about 13h 35m. If you're looking for the fastest trip, you can get there in just about 13h 35m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. When is the first coach from Mobile to Knoxville?

    The first coach to Knoxville from Mobile departs at 07:30. Times and services may vary during weekends and holidays.

  4. How far is Knoxville from Mobile by coach?

    The journey from Mobile to Knoxville by coach covers an approximate distance of 435 miles (701 km).

  5. Is there a way to reach Knoxville from Mobile without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
22/05
No data
23/05
US$108
Today
US$99
25/05
US$107
26/05
No data
27/05
No data
28/05
No data
29/05
No data
busbud logoThe cheapest trip from Mobile to Knoxville was searched and found on 24 May 2025 with a price of US$99

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to Knoxville as early as possible.

You can expect to pay from US$99 to US$108 for a bus ticket from Mobile to Knoxville based on the last 2 days. You can expect to find the cheapest price for the trip at US$107, which is on 2025-05-25.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mobile and Knoxville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Mobile to Knoxville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mobile to Knoxville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mobile to Knoxville.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Mobile by bus?

Bus from Mobile to Knoxville

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