Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Viale Toselli (Penny Market) | Terminal Bus Palermo | No tags | ||||
| Bus | Siena Train Station | Terminal Bus Palermo | No tags | ||||
| Bus | Viale Toselli (Penny Market) | Terminal Bus Palermo | No tags | ||||
| Bus | Siena Train Station | Terminal Bus Palermo | No tags | ||||
| Bus | Siena Train Station | Terminal Bus Palermo | No tags |
Compare 2 ways to travel from Siena to Palermo
Among the sustainable travel choices, the Bus stands out as a good way to reach Palermo. The journey takes about 16 hours and with fares starting at just £23, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average price£23 - £44 | Average duration16h | 15kg CO₂e | ||
Carpool | Average price£47 - £47 | Average duration13h 30m | 25kg CO₂e |
Where are the popular stops in Siena and Palermo?
Stops in Siena
- APiazza Antonio Gramsci, 53100 Siena SI, Italy
- B
Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy - C
Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy - D
Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy - E
Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy - F
Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
Compare bus companies
Based on 12289 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at £23
Frequently asked questions about travelling by bus from Siena to Palermo
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Siena to Palermo?
The cheapest coach tickets from Siena to Palermo start from £23. The average price for this route is around £33. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Siena to Palermo?
The average bus journey time from Siena to Palermo is 16h, covering a distance of 376 miles. The fastest bus can take you there in 16h and is operated by FlixBus.
Which bus companies service the Siena to Palermo route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Siena to Palermo?
The earliest bus departs from Siena to Palermo at 19:00. And the latest bus departs at 21:00.
What are the CO₂ emissions for the bus trip from Siena to Palermo?
A bus journey from Siena to Palermo produces an estimated 15 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Siena to Palermo was searched and found on 4 Mar 2026 with a price of £53To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Siena to Palermo as early as possible.
What's the cheapest way to go from Siena to Palermo?
The Bus is the cheapest travel choice for this destination
