Find coaches from Tupelo to Charlotte, NC

Next departures

Next departures from Tupelo to Charlotte on 13 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Tupelo (Brothers Quick Stop)
Charlotte (Freedom Dr)Cheapest
Greyhound Lines, Inc. + FlixBus
Tupelo (Brothers Quick Stop)
Charlotte Bus StationFastest
Greyhound Lines, Inc. + FlixBus
Tupelo (Brothers Quick Stop)
Charlotte Bus StationNo tags

Last refresh of the prices: Today at 11:28 CDT.

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Bus Tupelo to Charlotte, NC: Trip Overview

Average ticket priceUS$73
Average bus trip duration11h 55m
Number of daily buses3
Earliest bus departure10:55
Distance450 miles
Latest bus departure23:15

Tupelo to Charlotte Bus

With Busbud, comparing and booking tickets for a bus from Tupelo to Charlotte is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Tupelo to Charlotte will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Charlotte from Tupelo, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Tupelo - Charlotte, NC

  1. What's the distance between Tupelo and Charlotte by coach?

    The distance between Tupelo and Charlotte by coach is approximately 449 miles (725 km).

  2. How can I travel from Tupelo to Charlotte avoiding air travel?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/10
No data
09/10
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Today
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11/10
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12/10
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13/10
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14/10
US$75
15/10
No data
busbud logoThe cheapest trip from Tupelo to Charlotte, NC was searched and found on 14 Oct 2025 with a price of US$75

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Charlotte, NC as early as possible.

You can expect to pay from US$75 to US$75 for a bus ticket from Tupelo to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at US$75, which is on 2025-10-14.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Tupelo to Charlotte.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Tupelo to Charlotte, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Tupelo to Charlotte.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tupelo to Charlotte.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Tupelo by bus?

Bus from Charlotte, NC to Tupelo

Why choose Busbud?

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