Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Boston (South Station) | Bus station | CheapestFastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 151 Steel Pl, Cambridge | Bus station | No tags |
Last refresh of the prices: Last Thursday at 9:17 PM EST.
Compare 2 ways to travel from Boston to Florence
Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 1 day, 4 hours 15 minutes and with fares starting at just R 1 481, it presents an excellent value for a comfortable ride.
Where are the popular stops in Boston and Florence?
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA - D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
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Frequently asked questions about travelling from Boston, MA, US to Florence, SC, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Boston to Florence?
The cheapest bus tickets from Boston to Florence start at R 1 481. The average price for this route is around R 2 536. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Boston to Florence?
The average bus journey time from Boston to Florence is 1d 4h, covering a distance of 1179 km. The fastest bus gets you there in 18h 30m and is operated by Greyhound.
Which bus companies service the Boston to Florence route?
What is the earliest and latest departure time for the bus from Boston to Florence?
The earliest bus departs from Boston to Florence at 01:30. And the latest bus departs at 21:50.
What are the CO₂ emissions for the bus trip from Boston to Florence?
A bus trip from Boston to Florence produces an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Boston to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11504 reviews.
Which bus company has the best Wi-Fi from Boston to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Boston to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Boston to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on 14 Dec 2025 with a price of R 1 574To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Florence, SC, US as early as possible.
You can expect to pay from R 1 574 to R 3 709 for a bus ticket from Boston, MA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 741, which is on 2025-12-19.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Boston, MA, US to Florence, SC, US?
The bus is the cheapest travel choice for this destination
