How much is the bus ticket from Boston to Florence?

The cheapest bus tickets from Boston to Florence start from $121. The average price for this route is around $185. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Boston to Florence?

The average bus trip duration from Boston to Florence is 1d 4h, covering a distance of 731 miles (1178 km). The quickest bus can get you there in 19h and is operated by Greyhound .

Which bus companies service the Boston to Florence route?

Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Boston to Florence?

The earliest bus departs from Boston to Florence at 1:30am. And the latest bus departs at 9:50pm.

What are the CO₂ emissions for the bus trip from Boston to Florence?

A bus trip from Boston to Florence generates an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Boston to Florence?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11638 reviews.

Which bus company has the best Wi-Fi from Boston to Florence?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Boston to Florence?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Boston to Florence?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Boston to Florence from $156 | Refundable Tickets

Next bus departures

Next departures for Boston to Florence on December 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:45pm	Boston (South Station)	19h	11:45am	Bus station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	9:50pm	Boston (South Station)	1d 7h	5:45am	Florence, SC	No tags
FlixBus + Greyhound Lines, Inc.	Bus	8:55pm	Brookline	1d 8h	5:45am	Florence, SC	No tags

Next departures for Boston to Florence on December 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	8:55pm	Brookline	1d 8h	5:45am	Florence, SC	Cheapest
	Bus	4:45pm	Boston (South Station)	19h	11:45am	Bus station	Fastest
	Bus	10:15am	Boston (South Station)	19h 30m	5:45am	Florence, SC	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:50pm	Boston (South Station)	1d 7h	5:45am	Florence, SC	No tags
FlixBus + Greyhound Lines, Inc.	Bus	1:30am	Brookline	1d 10h	11:45am	Bus station	No tags

Last refresh of the prices: Yesterday at 2:50 PM EST.

Compare 2 ways to go from Boston to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 1 day, 4 hours 15 minutes and with fares starting at just $121, it presents an excellent value for a comfortable ride.

6bus per day

1d 4hAverage Duration

731 milesDistance

29kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$121 - $311	Average Duration1d 4h	CO₂ emissions 29kg CO₂e
Train	Average Price$140 - $2,029	Average Duration18h	CO₂ emissions 107kg CO₂e

Where are the popular stops in Boston and Florence?

Stops in Boston

A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA
Visit page
B
North Station
100 Legends Way, Boston, MA 02114, USA
Visit page
C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA
D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA
E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA
F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

FlixBus

3.5/511,732 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,451 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Boston, MA, US to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Boston to Florence?
The cheapest bus tickets from Boston to Florence start from $121. The average price for this route is around $185. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Boston to Florence?
The average bus trip duration from Boston to Florence is 1d 4h, covering a distance of 731 miles (1178 km). The quickest bus can get you there in 19h and is operated by Greyhound.
Which bus companies service the Boston to Florence route?
Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Boston to Florence?
The earliest bus departs from Boston to Florence at 1:30am. And the latest bus departs at 9:50pm.
What are the CO₂ emissions for the bus trip from Boston to Florence?
A bus trip from Boston to Florence generates an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Boston to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11638 reviews.
Which bus company has the best Wi-Fi from Boston to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Boston to Florence?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Boston to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/23

$247

12/24

$253

Today

$189

12/26

$230

12/27

$232

12/28

$171

12/29

$156

12/30

$165

The cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on Dec 29, 2025 with a price of $156

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Florence, SC, US, as early as possible.

You can expect to pay from $156 to $271 for a bus ticket from Boston, MA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $156 which is on 2025-12-29.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.