Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Boston (South Station) | Florence, SC | ||||
FlixBus + Greyhound | Bus | Brookline | Florence, SC | ||||
FlixBus + Greyhound | Bus | Boston (South Station) | Florence, SC | ||||
FlixBus + Greyhound | Bus | 151 Steel Pl, Cambridge | Bus station | ||||
FlixBus + Greyhound | Bus | Boston (South Station) | Bus station |
Compare 2 ways to go from Boston to Florence
Among the sustainable travel choices, the Train stands out as a good way to reach Florence. The journey takes about 18 hours 10 minutes and with fares starting at just CZK 2,950, it presents an excellent value for a comfortable ride.
Where are the popular stops in Boston and Florence?
Stops in Boston
- A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA - B
North Station
100 Legends Way, Boston, MA 02114, USA - C
Riverside Bus Station
335 Grove St, Auburndale, MA 02466 - D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Frequently asked questions about traveling from Boston, MA, US to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Boston to Florence?
The cheapest bus tickets from Boston to Florence start from CZK 2,132. The average price for this route is around CZK 2,763. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Boston to Florence?
The average bus trip duration from Boston to Florence is 1d 4h, covering a distance of 732 miles (1181 km). The quickest bus can get you there in 18h 30m and is operated by FlixBus.
Which bus companies service the Boston to Florence route?
What is the earliest and latest departure time for the bus from Boston to Florence?
The earliest bus departs from Boston to Florence at 1:30am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Boston to Florence?
A bus trip from Boston to Florence generates an estimated 29.51415 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Boston to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12791 reviews.
Which bus company has the best Wi-Fi from Boston to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Boston to Florence?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Boston to Florence?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on Jun 11, 2026 with a price of CZK 1,851To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Florence, SC, US, as early as possible.
You can expect to pay from CZK 1,851 to CZK 4,472 for a bus ticket from Boston, MA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at CZK 1,904 which is on 2026-06-15.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Boston, MA, US to Florence, SC, US?
The Bus is the cheapest travel choice for this destination
