- Buffalo to St. Louis buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Niagara Frontier Transportation Authority | Gateway Station | No tags | ||||
FlixBus + Greyhound | Bus | Buffalo (BUF) Airport | Gateway Station | No tags | ||||
Greyhound + FlixBus | Bus | Buffalo (BUF) Airport | Gateway Station | No tags | ||||
FlixBus + Greyhound | Bus | Niagara Frontier Transportation Authority | Gateway Station | No tags | ||||
FlixBus + Greyhound | Bus | Buffalo (BUF) Airport | Gateway Station | No tags |
Compare 2 ways to go from Buffalo to St. Louis
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach St. Louis. The journey takes about 20 hours 28 minutes and with fares starting at just $193, it presents an excellent value for a comfortable ride.
1train per day
20h 28mAverage Duration
668 milesDistance
98kgCO₂ emissions
Where are the popular stops in Buffalo and St. Louis?
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Compare bus companies
US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about traveling from Buffalo, NY to St. Louis by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/23
$115
11/24
No data
Today
$112
11/26
$152
11/27
No data
11/28
No data
11/29
No data
11/30
$342
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to St. Louis, as early as possible.
You can expect to pay from $112 to $342 for a bus ticket from Buffalo, NY to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $152 which is on 2025-11-26.







