Find coaches from Chicago to Tupelo

Next departures

Next departures from Chicago to Tupelo on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Chicago 95Th & Dan Ryan
Tupelo (Brothers Quick Stop)Cheapest
Greyhound Lines, Inc.
Downtown Greyhound Station
Tupelo (Brothers Quick Stop)Fastest
FlixBus + Greyhound Lines, Inc.
Downtown Greyhound Station
Tupelo (Brothers Quick Stop)No tags
Greyhound Lines, Inc.
537-517 W. Jackson Blvd
Tupelo (Brothers Quick Stop)No tags
FlixBus + Greyhound Lines, Inc.
Downtown Greyhound Station
Tupelo (Brothers Quick Stop)No tags

Last refresh of the prices: Yesterday at 12:16 AM CDT.

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Get from Chicago to Tupelo

busbud logoThis route is served by bus only

The journey takes about 20 hours 55 minutes, and with fares starting at just US$73, it presents an excellent value for a comfortable ride.

8bus per day
20h 55mAverage duration
838 kmDistance
21kgCO₂ emissions

Bus Chicago to Tupelo: Trip Overview

Average ticket priceUS$102
Average bus trip duration20h 55m
Number of daily buses8
Earliest bus departure00:30
Distance838 km
Latest bus departure23:59

Chicago to Tupelo Bus

With Busbud, comparing and booking tickets for a bus from Chicago to Tupelo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Chicago to Tupelo.

Discover how much the bus trip from Chicago to Tupelo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Chicago - Tupelo

  1. How much does a bus ticket from Chicago to Tupelo cost?

    The bus ticket price from Chicago to Tupelo starts at US$73. The best way to find cheap bus tickets from Chicago to Tupelo is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Chicago to Tupelo?

    The average travel time between Chicago and Tupelo is around 20h 55m, although the fastest bus will take about 12h 10m. This is the time it takes to travel the 853 km that separates the two cities.

  3. How many daily bus connections are there between Chicago and Tupelo?

    The number of buses from Chicago to Tupelo can differ depending on the day of the week. On average, there are 8 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Chicago to Tupelo by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Chicago to Tupelo?

    When taking the bus from Chicago to Tupelo, you can travel comfortably and safely with Greyhound, FlixBus.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$100
29/10
No data
Today
US$102
31/10
US$86
01/11
US$93
02/11
No data
03/11
No data
04/11
US$85
busbud logoThe cheapest trip from Chicago to Tupelo was searched and found on 04 Nov 2025 with a price of US$85

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Tupelo as early as possible.

You can expect to pay from US$85 to US$147 for a bus ticket from Chicago to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at US$85, which is on 2025-11-04.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Chicago to Tupelo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Chicago to Tupelo.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Chicago to Tupelo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Chicago to Tupelo while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Chicago by bus?

Bus from Tupelo to Chicago

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