- Chicago to Tupelo buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Bus | 537-517 W. Jackson Blvd | Tupelo (Brothers Quick Stop) | No tags | ||||
FlixBus + Greyhound | Bus | Chicago 95Th & Dan Ryan | Tupelo (Brothers Quick Stop) | No tags | ||||
![]() | Bus | 537-517 W. Jackson Blvd | Tupelo (Brothers Quick Stop) | No tags | ||||
![]() | Bus | Downtown Greyhound Station | Tupelo (Brothers Quick Stop) | No tags | ||||
![]() | Bus | Chicago 95Th & Dan Ryan | Tupelo (Brothers Quick Stop) | No tags |
Get from Chicago to Tupelo
This route is served by bus only
The journey takes about 20 hours 55 minutes and with fares starting at just $89, it presents an excellent value for a comfortable ride.
7bus per day
20h 55mAverage Duration
520 milesDistance
21kgCO₂ emissions
Compare bus companies
US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about traveling from Chicago to Tupelo by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
$144
11/20
$154
Today
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11/22
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11/23
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11/24
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11/25
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11/26
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To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Tupelo, as early as possible.







