Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 537-517 W. Jackson Blvd | Tupelo (Brothers Quick Stop) | No tags | ||||
Greyhound + FlixBus | Bus | Chicago 95Th & Dan Ryan | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | 537-517 W. Jackson Blvd | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Chicago 95Th & Dan Ryan | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Downtown Greyhound Station | Tupelo (Brothers Quick Stop) | No tags |
Get from Chicago to Tupelo
The journey takes about 16 hours 15 minutes, and with fares starting at just £69, it presents an excellent value for a comfortable ride.
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Frequently asked questions about travelling by bus from Chicago to Tupelo
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Chicago to Tupelo?
The cheapest coach tickets from Chicago to Tupelo start from £69. The average price for this route is around £85. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Chicago to Tupelo?
The average bus journey time from Chicago to Tupelo is 16h 15m, covering a distance of 520 miles. The fastest bus can take you there in 12h 10m and is operated by Greyhound.
Which bus companies service the Chicago to Tupelo route?
What is the earliest and latest departure time for the bus from Chicago to Tupelo?
The earliest bus departs from Chicago to Tupelo at 00:30. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from Chicago to Tupelo?
A bus journey from Chicago to Tupelo produces an estimated 21 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Chicago to Tupelo?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which company has the best Wi-Fi from Chicago to Tupelo?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Chicago to Tupelo?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Tupelo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Tupelo was searched and found on 26 Nov 2025 with a price of £152To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Tupelo as early as possible.
