Bus Tickets from Chicago to Tupelo

Previously seen trips

Next departures for Chicago to Tupelo on October 8
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
537-517 W. Jackson Blvd
Tupelo (Brothers Quick Stop)No tags
Greyhound + FlixBus
Chicago 95Th & Dan Ryan
Tupelo (Brothers Quick Stop)No tags
Greyhound
537-517 W. Jackson Blvd
Tupelo (Brothers Quick Stop)No tags
Greyhound
Chicago 95Th & Dan Ryan
Tupelo (Brothers Quick Stop)No tags
Greyhound
Downtown Greyhound Station
Tupelo (Brothers Quick Stop)No tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Chicago to Tupelo: Trip Overview

Average Ticket PriceUS$99
Average Bus Trip Duration15h 15m
Number of daily buses8
Earliest bus departure12:30am
Distance854 km
Latest bus departure11:59pm

Chicago to Tupelo Bus

With Busbud, comparing and booking tickets for a bus from Chicago to Tupelo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Chicago to Tupelo.

Discover how much the bus trip from Chicago to Tupelo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Chicago - Tupelo

  1. How far is Chicago from Tupelo?

    The distance covered from Chicago to Tupelo is 853 km (529 miles).

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-06
US$120
10-07
US$90
Today
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10-09
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10-10
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10-11
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10-12
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10-13
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busbud logoThe cheapest trip from Chicago to Tupelo was searched and found on Oct 7, 2025 with a price of US$90

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Tupelo, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Chicago to Tupelo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Chicago to Tupelo.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Chicago to Tupelo will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Chicago to Tupelo while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Chicago by bus?

Bus from Tupelo to Chicago

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