Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Midway Truck Plaza Bus Stop | Downtown Greyhound Station | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Midway Truck Plaza Bus Stop | Downtown Greyhound Station | Fastest | ||||
| Bus | Midway Truck Plaza Bus Stop | 537-517 W. Jackson Blvd | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Columbia Wabash Station | Downtown Greyhound Station | No tags | ||||
| Bus | Columbia Wabash Station | Downtown Greyhound Station | No tags |
Last refresh of the prices: Today at 2:23 PM CST.
Get from Columbia to Chicago
The journey takes about 11 hours 35 minutes, and with fares starting at just R 933, it presents an excellent value for a comfortable ride.
Where are the popular stops in Columbia and Chicago?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- B
Chicago O'Hare International Airport
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Based on 87433 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 941
Greyhound Columbia Chicago recent customer reviews
I will never rude it again I had to call off work this morning because I had 3 delays on my busses which is very sad
Shekena W.
Bus was wery dirty
Magdalena C.
I waited at a transfer for 3 hours because nobody could find a driver
Nikole G.
Frequently asked questions about travelling from Columbia, MO to Chicago by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Columbia to Chicago?
The cheapest bus tickets from Columbia to Chicago start at R 933. The average price for this route is around R 1 570. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Columbia to Chicago?
The average bus journey time from Columbia to Chicago is 11h 35m, covering a distance of 504 km. The fastest bus gets you there in 12h 20m and is operated by Greyhound.
Which bus companies service the Columbia to Chicago route?
Several major bus companies operate on this route with 11 buses available per day.
What is the earliest and latest departure time for the bus from Columbia to Chicago?
The earliest bus departs from Columbia to Chicago at 08:30. And the latest bus departs at 20:35.
What are the CO₂ emissions for the bus trip from Columbia to Chicago?
A bus trip from Columbia to Chicago produces an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Columbia, MO to Chicago was searched and found on 14 Dec 2025 with a price of R 947To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbia, MO to Chicago as early as possible.
You can expect to pay from R 947 to R 2 789 for a bus ticket from Columbia, MO to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 947, which is on 2025-12-18.
