Find coaches from Columbia, MO to Chicago

Find affordable coach tickets from Columbia, MO to Chicago with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.
Sat28 Jun
from US$88
Sun29 Jun
from US$80
Mon30 Jun
from US$102
Tue1 Jul
from US$71
Wed2 Jul
Thu3 Jul
from US$64
Fri4 Jul
Sat5 Jul

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 29 June at
    Departure city: Columbia
    Departure location: Midway Truck Plaza Bus Stop
    Arrival time: 29 June at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 29 June at
    Departure city: Columbia
    Departure location: Midway Truck Plaza Bus Stop
    Arrival time: 29 June at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 29 June at
    Departure city: Columbia
    Departure location: Midway Truck Plaza Bus Stop
    Arrival time: 30 June at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 29 June at
    Departure city: Columbia
    Departure location: Columbia Wabash Station
    Arrival time: 29 June at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 29 June at
    Departure city: Columbia
    Departure location: Midway Truck Plaza Bus Stop
    Arrival time: 30 June at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Columbia to Chicago: Trip Overview

Average ticket priceUS$91
Average bus trip duration17h 25m
Number of daily buses9
Earliest bus departure08:30
Distance318 miles
Latest bus departure20:35

Columbia to Chicago Bus

With Busbud, comparing and booking tickets for a bus from Columbia to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Columbia to Chicago will be provided by the most trusted bus companies.

Discover how much the bus trip from Columbia to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Columbia, MO - Chicago

  1. How far is Chicago from Columbia by coach?

    The distance between Columbia and Chicago by coach is approximately 318 miles (512 km).

  2. Is there a way to reach Chicago from Columbia without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
24/06
US$136
25/06
US$102
Today
US$109
27/06
No data
28/06
US$118
29/06
US$147
30/06
US$107
01/07
US$64
busbud logoThe cheapest trip from Columbia to Chicago was searched and found on 1 Jul 2025 with a price of US$64

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbia to Chicago as early as possible.

You can expect to pay from US$64 to US$156 for a bus ticket from Columbia to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$64, which is on 2025-07-01.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Columbia to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Columbia to Chicago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Columbia to Chicago will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Columbia to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Columbia by bus?

Bus from Columbia to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Columbia

Buses Leaving from Columbia

Buses Going to Columbia

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago