Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus
| Columbia Wabash Station | Downtown Greyhound Station | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Midway Truck Plaza Bus Stop | Chicago 95Th & Dan Ryan | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Midway Truck Plaza Bus Stop | Downtown Greyhound Station | No tags | ||||
 | Bus
| Midway Truck Plaza Bus Stop | 537-517 W. Jackson Blvd | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Midway Truck Plaza Bus Stop | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Columbia Wabash Station | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Midway Truck Plaza Bus Stop | Chicago 95Th & Dan Ryan | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Columbia Wabash Station | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Today at 12:46 AM CDT.
Get from Columbia to Chicago
The journey takes about 9 hours 55 minutes and with fares starting at just CA$75, it presents an excellent value for a comfortable ride.
Bus stations and stops in Columbia and Chicago
Stops in Chicago
- A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA - C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Columbia Chicago recent customer reviews
I will never rude it again I had to call off work this morning because I had 3 delays on my busses which is very sad
Shekena W.
Bus was wery dirty
Magdalena C.
I waited at a transfer for 3 hours because nobody could find a driver
Nikole G.
Frequently asked questions about traveling from Columbia, MO to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Columbia to Chicago?
The cheapest bus tickets from Columbia to Chicago start from CA$75. The average price for this route is around CA$113. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Columbia to Chicago?
The average bus trip duration from Columbia to Chicago is 9h 55m, covering a distance of 318 miles (512 km). The quickest bus can get you there in 16h 40m and is operated by Greyhound.
Which bus companies service the Columbia to Chicago route?
Several major bus companies operate on this route with 11 buses available per day.
What is the earliest and latest departure time for the bus from Columbia to Chicago?
The earliest bus departs from Columbia to Chicago at 8:30am. And the latest bus departs at 8:35pm.
What are the CO₂ emissions for the bus trip from Columbia to Chicago?
A bus trip from Columbia to Chicago generates an estimated 12.788 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Columbia, MO to Chicago was searched and found on Sep 21, 2026 with a price of CA$91To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbia, MO to Chicago, as early as possible.
You can expect to pay from CA$91 to CA$132 for a bus ticket from Columbia, MO to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at CA$91 which is on 2026-09-21.
