Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus
| Midway Truck Plaza Bus Stop | Chicago 95Th & Dan Ryan | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Midway Truck Plaza Bus Stop | Chicago 95Th & Dan Ryan | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Midway Truck Plaza Bus Stop | Downtown Greyhound Station | No tags | ||||
 | Bus
| Midway Truck Plaza Bus Stop | 537-517 W. Jackson Blvd | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Midway Truck Plaza Bus Stop | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Columbia Wabash Station | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Columbia Wabash Station | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Columbia Wabash Station | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Yesterday at 10:05 AM CDT.
Get from Columbia to Chicago
The journey takes about 12 hours 5 minutes, and with fares starting at just $79, it presents an excellent value for a comfortable ride.
Bus stations and stops in Columbia and Chicago
Stops in Chicago
- A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA - C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Based on 88238 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $87
Greyhound Columbia Chicago recent customer reviews
I will never rude it again I had to call off work this morning because I had 3 delays on my busses which is very sad
Shekena W.
Bus was wery dirty
Magdalena C.
I waited at a transfer for 3 hours because nobody could find a driver
Nikole G.
Frequently asked questions about travelling from Columbia, MO to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Columbia to Chicago?
The cheapest bus tickets from Columbia to Chicago start from $79. The average price for this route is around $121. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Columbia to Chicago?
The average bus travel time from Columbia to Chicago is 12h 5m, covering a distance of 512 km. The quickest bus can get you there in 16h 40m and is operated by Greyhound.
Which bus companies service the Columbia to Chicago route?
Several major bus companies operate on this route with 12 buses available per day.
What are the earliest and latest departure times for the bus from Columbia to Chicago?
The earliest bus departs from Columbia to Chicago at 8:30am. And the latest bus departs at 8:35pm.
What are the CO₂ emissions for the bus trip from Columbia to Chicago?
A bus trip from Columbia to Chicago generates an estimated 12.786875 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Columbia, MO to Chicago was searched and found on Oct 15, 2026 with a price of $109To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbia, MO to Chicago, as early as possible.
You can expect to pay from $109 to $225 for a bus ticket from Columbia, MO to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $150 which is on 2026-10-18.
